Obesity, Preserved Ejection Fraction Heart Failure, and Left Ventricular Remodeling

被引：12

作者：

Stencel, Jason ^{[1
]}

Alai, Hamid R. ^{[1
,2
]}

Dhore-patil, Aneesh ^{[1
]}

Urina-Jassir, Daniela ^{[1
]}

Le Jemtel, Thierry H. ^{[1
]}

机构：

[1] Tulane Univ, Heart & Vasc Inst, John W Deming Dept Med, Sect Cardiol,Sch Med, New Orleans, LA 70112 USA

[2] Southeast Louisiana VA Healthcare Syst SLVHCS, New Orleans, LA 70119 USA

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 09期

关键词：

obesity; HFpEF; metabolic bariatric surgery; left ventricular mass; epicardial adipose tissue; BODY-MASS INDEX; EPICARDIAL ADIPOSE-TISSUE; CORONARY MICROVASCULAR DYSFUNCTION; ARTERY RISK DEVELOPMENT; BARIATRIC SURGERY; DIASTOLIC DYSFUNCTION; EXERCISE INTOLERANCE; WEIGHT-LOSS; ENDOTHELIAL DYSFUNCTION; OLDER PATIENTS;

D O I：

10.3390/jcm12093341

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Owing to the overwhelming obesity epidemic, preserved ejection fraction heart failure commonly ensues in patients with severe obesity and the obese phenotype of preserved ejection fraction heart failure is now commonplace in clinical practice. Severe obesity and preserved ejection fraction heart failure share congruent cardiovascular, immune, and renal derangements that make it difficult to ascertain whether the obese phenotype of preserved ejection fraction heart failure is the convergence of two highly prevalent conditions or severe obesity enables the development and progression of the syndrome of preserved ejection fraction heart failure. Nevertheless, the obese phenotype of preserved ejection fraction heart failure provides a unique opportunity to assess whether sustained and sizeable loss of excess body weight via metabolic bariatric surgery reverses the concentric left ventricular remodeling that patients with preserved ejection fraction heart failure commonly display.

引用

页数：21

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