Total Synthesis of Okaspirodiol

被引：0
|
作者：
Madasu, Madhu [1 ]
Mohapatra, Debendra K. [1 ]
机构：
[1] Indian Inst Chem Technol, Dept Organ Synth & Proc Chem, CSIR, Hyderabad 500007, India
来源：
CHEMISTRYSELECT | 2023年 / 8卷 / 13期
关键词：
Acid-catalyzed spiroketalization; Okaspirodiol; Sharpless asymmetric epoxidation; Spiroketal; Wittig reaction; ENANTIOSELECTIVE SYNTHESIS; BIOLOGICAL-ACTIVITY; SECONDARY ALCOHOLS; NATURAL-PRODUCTS; REVEROMYCIN-A; BIOSYNTHESIS; CHEMISTRY; GROWTH;
D O I：
10.1002/slct.202300352
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The asymmetric total synthesis of okaspirodiol was achieved following Sharpless asymmetric epoxidation, Gilman reaction, Wittig reaction, Horner-Wadsworth-Emmons olefination, and coupling of alkyne with the aldehyde, and acid-catalyzed spiroketalization as key reactions.
引用
收藏
页数：7
相关论文
共 50 条
  • [41] Total Synthesis of Gabosine H
    Prasad, Kavirayani R.
    Kumar, S. Mothish
    SYNLETT, 2011, (11) : 1602 - 1604
  • [42] Enantioselective Total Synthesis of (-)-Diversonol
    Tietze, Lutz F.
    Jackenkroll, Stefan
    Raith, Christian
    Spiegl, Dirk A.
    Reiner, Johannes R.
    Campos, Maria Claudia Ochoa
    CHEMISTRY-A EUROPEAN JOURNAL, 2013, 19 (15) : 4876 - 4882
  • [43] Bioinspired Total Synthesis of Sespenine
    Sun, Yu
    Chen, Pengxi
    Zhang, Deliang
    Baunach, Martin
    Hertweck, Christian
    Li, Ang
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 53 (34) : 9012 - 9016
  • [44] Total Synthesis of Sporolide B
    Nicolaou, K. C.
    Tang, Yefeng
    Wang, Jianhua
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (19) : 3449 - 3453
  • [45] Total synthesis of inubosin B
    Hamissa, Mohamed Farouk
    Niederhafner, Petr
    Safarik, Martin
    Telus, Marta
    Kolarova, Lenka
    Koutna, Leah
    Sestakova, Hana
    Soucek, Radko
    Sebestik, Jaroslav
    TETRAHEDRON LETTERS, 2020, 61 (52)
  • [46] Advances in the Total Synthesis of Aflatoxins
    Yang, Liyan
    Wang, Zhonglei
    FRONTIERS IN CHEMISTRY, 2021, 9
  • [47] Enantioselective Total Synthesis of (-)-Jiadifenolide
    Xu, Jing
    Trzoss, Lynnie
    Chang, Weng K.
    Theodorakis, Emmanuel A.
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (16) : 3672 - 3676
  • [48] Biomimetic Total Synthesis of (±)-Pallavicinolide A
    Dong, Jia-Qiang
    Wong, Henry N. C.
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (13) : 2351 - 2354
  • [49] Total Synthesis of Sch 725674
    Vaithegi, Kannan
    Prasad, Kavirayani R.
    TETRAHEDRON, 2018, 74 (20) : 2488 - 2492
  • [50] Methoxatin as a Target in Total Synthesis
    Schroeder, Birte
    Gaich, Tanja
    SYNTHESIS-STUTTGART, 2017, 49 (08): : 1746 - 1756
12345