Total Synthesis of Okaspirodiol

被引：0
|
作者：
Madasu, Madhu [1 ]
Mohapatra, Debendra K. [1 ]
机构：
[1] Indian Inst Chem Technol, Dept Organ Synth & Proc Chem, CSIR, Hyderabad 500007, India
来源：
CHEMISTRYSELECT | 2023年 / 8卷 / 13期
关键词：
Acid-catalyzed spiroketalization; Okaspirodiol; Sharpless asymmetric epoxidation; Spiroketal; Wittig reaction; ENANTIOSELECTIVE SYNTHESIS; BIOLOGICAL-ACTIVITY; SECONDARY ALCOHOLS; NATURAL-PRODUCTS; REVEROMYCIN-A; BIOSYNTHESIS; CHEMISTRY; GROWTH;
D O I：
10.1002/slct.202300352
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The asymmetric total synthesis of okaspirodiol was achieved following Sharpless asymmetric epoxidation, Gilman reaction, Wittig reaction, Horner-Wadsworth-Emmons olefination, and coupling of alkyne with the aldehyde, and acid-catalyzed spiroketalization as key reactions.
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页数：7
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