A Study on Micronuclei in Exfoliated Buccal Epithelial Smears to Detect Epithelial Changes in Patients Undergoing Panoramic Radiography

被引：0
|
作者：
Sreeshyla, Huchanahalli Sheshanna [1 ]
Aishwarya, Ramesh
Hegde, Usha [1 ]
Muralidhar, Nitin Vemula [2 ]
Nitin, Priyanka [1 ]
Patil, Karthekeya [3 ]
Harshitha, Ninganna
Govindarajan, Shruti [1 ]
机构：
[1] JSS Acad Higher Educ & Res, JSS Dent Coll & Hosp, Dept Oral Pathol & Microbiol, Mysore 570015, Karnataka, India
[2] JSS Acad Higher Educ & Res, JSS Dent Coll & Hosp, Dept Orthodont, Mysore, Karnataka, India
[3] JSS Acad Higher Educ & Res, JSS Dent Coll & Hosp, Dept Oral Med & Radiol, Mysore, Karnataka, India
来源：
BIOMEDICAL AND BIOTECHNOLOGY RESEARCH JOURNAL | 2023年 / 7卷 / 03期
关键词：
Buccal epithelial cells; cytogenetic changes; exfoliative cytology; micronuclei; panoramic radiography; IONIZING-RADIATION; MUCOSA CELLS; ORAL-MUCOSA; X-RAYS; CYTOTOXICITY; MUTAGENICITY; LYMPHOCYTES; DAMAGE;
D O I：
10.4103/bbrj.bbrj_127_23
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Background: Ionizing radiation can cause chromosomal aberrations and micronuclei (MN) formation in the cell cytoplasm, and a research study was conducted to assess the genotoxic effects of panoramic radiation. Methods: Cytological smears were prepared from the buccal mucosa of 60 patients between the age group of 10-40 years before and 10 days after exposure to panoramic radiation and were stained with Giemsa. The sections were studied for the frequency of MN before and after exposure to radiation. Results: There was a statistically significant increase in the cells containing MN (MCF) and total MN count after exposure to the radiation in comparison to before exposure. There was no correlation of MN and MCF with age and gender. Conclusion: This data suggests that there is a need to use panoramic radiographs cautiously, only when it is highly necessary.
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页码：387 / 390
页数：4
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