Green Synthesis of Therapeutically Active Heterocyclic Scaffolds: A Review

被引:0
|
作者
Mohammed, Tasneem [1 ]
Nasreen, Aayesha [2 ]
Alqahtani, Yahya S. [3 ]
Shaikh, Ibrahim Ahmed [4 ]
Iqubal, Shakeel [1 ]
Fathima, Shaik Honey [5 ]
Khan, Aejaz A. [1 ]
机构
[1] Ibn Sina Natl, Dept Gen Sci, Coll Med Studies, Jeddah 21418, Saudi Arabia
[2] Jazan Univ, Coll Sci, Dept Chem, Jazan 828172820, Saudi Arabia
[3] Najran Univ, Coll Pharm, Dept Pharmaceut Chem, Najran 66462, Saudi Arabia
[4] Najran Univ, Coll Pharm, Dept Pharmacol, Najran 66462, Saudi Arabia
[5] Koneru Lakshmaiah Educ Fdn, Coll Engn, Dept Engn Math, Hyderabad 500075, Telangana, India
关键词
Green Synthesis; Heterocyclic Scaffolds; Natural Products; Therapeutic Use; Eco-friendly; ONE-POT SYNTHESIS; SOLVENT-FREE SYNTHESIS; HIGHLY EFFICIENT; CATALYST-FREE; FUNCTIONALIZED 1,4-DIHYDROPYRIDINES; PRIVILEGED STRUCTURES; MEDICINAL CHEMISTRY; SULFONIC-ACID; IONIC LIQUID; DERIVATIVES;
D O I
10.1166/sam.2023.4477
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Green chemistry lowers chemical hazards during chemical design, manufacture, and use. By using cleaner solvents, catalysts, and reaction conditions, this technique reduces environmental pollution and boosts atom economy and energy efficiency. Rapid industrialization and urbanization are causing significant harm to our environment by releasing a lot of dangerous and undesired chemicals, gases, or other pollutants. The secrets hidden in nature and its by-products must now be discovered by us in order to enhance the synthesis of physiologically significant moieties and foster its growth. Heterocyclic compounds and its derivatives exhibit various biological potential like anticancer, antimicrobial, anticonvulsant, analgesic, antitubercular, antiinflammatory and cardiovascular activities. This IP:make them203.8.109.20good On: candidatesTue, 05 forSep future2023 medication04:34:07 discovery and give them the potential to be an arsenal for treating diseases. This article provides an overview of the numerous environCopyright: American Scientific Publishers mentally friendly and green synthetic techniques used to create diverse physiologically significant heterocyclic Delivered by Ingenta scaffolds in the period 2002-2022. It is anticipated that this compilation of pertinent information will be of significance and practical value to chemists specializing in organic and pharmaceutical domains, potentially stimulating additional advancements in reaction development within this captivating area of study.
引用
收藏
页码:725 / 747
页数:23
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