Green Synthesis of Therapeutically Active Heterocyclic Scaffolds: A Review

被引:0
|
作者
Mohammed, Tasneem [1 ]
Nasreen, Aayesha [2 ]
Alqahtani, Yahya S. [3 ]
Shaikh, Ibrahim Ahmed [4 ]
Iqubal, Shakeel [1 ]
Fathima, Shaik Honey [5 ]
Khan, Aejaz A. [1 ]
机构
[1] Ibn Sina Natl, Dept Gen Sci, Coll Med Studies, Jeddah 21418, Saudi Arabia
[2] Jazan Univ, Coll Sci, Dept Chem, Jazan 828172820, Saudi Arabia
[3] Najran Univ, Coll Pharm, Dept Pharmaceut Chem, Najran 66462, Saudi Arabia
[4] Najran Univ, Coll Pharm, Dept Pharmacol, Najran 66462, Saudi Arabia
[5] Koneru Lakshmaiah Educ Fdn, Coll Engn, Dept Engn Math, Hyderabad 500075, Telangana, India
关键词
Green Synthesis; Heterocyclic Scaffolds; Natural Products; Therapeutic Use; Eco-friendly; ONE-POT SYNTHESIS; SOLVENT-FREE SYNTHESIS; HIGHLY EFFICIENT; CATALYST-FREE; FUNCTIONALIZED 1,4-DIHYDROPYRIDINES; PRIVILEGED STRUCTURES; MEDICINAL CHEMISTRY; SULFONIC-ACID; IONIC LIQUID; DERIVATIVES;
D O I
10.1166/sam.2023.4477
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
Green chemistry lowers chemical hazards during chemical design, manufacture, and use. By using cleaner solvents, catalysts, and reaction conditions, this technique reduces environmental pollution and boosts atom economy and energy efficiency. Rapid industrialization and urbanization are causing significant harm to our environment by releasing a lot of dangerous and undesired chemicals, gases, or other pollutants. The secrets hidden in nature and its by-products must now be discovered by us in order to enhance the synthesis of physiologically significant moieties and foster its growth. Heterocyclic compounds and its derivatives exhibit various biological potential like anticancer, antimicrobial, anticonvulsant, analgesic, antitubercular, antiinflammatory and cardiovascular activities. This IP:make them203.8.109.20good On: candidatesTue, 05 forSep future2023 medication04:34:07 discovery and give them the potential to be an arsenal for treating diseases. This article provides an overview of the numerous environCopyright: American Scientific Publishers mentally friendly and green synthetic techniques used to create diverse physiologically significant heterocyclic Delivered by Ingenta scaffolds in the period 2002-2022. It is anticipated that this compilation of pertinent information will be of significance and practical value to chemists specializing in organic and pharmaceutical domains, potentially stimulating additional advancements in reaction development within this captivating area of study.
引用
收藏
页码:725 / 747
页数:23
相关论文
共 50 条
  • [21] Recent Updates of Ionic Liquids as a Green and Eco-friendly Catalyst in the Synthesis of Heterocyclic Compounds: A Mini-Review
    Orynbaevna, Abilkasova Sandugash
    Ospanakunovna, Bugubaeva Gulnar
    Mautenovna, Kalimoldina Laila
    Namatzhanovish, Alipbayev Amanbol
    Asilbek, Kozybayev
    Sabitovna, Yegeubayeva Salamat
    IRANIAN JOURNAL OF CATALYSIS, 2023, 13 (04): : 387 - 436
  • [22] Silica-based nanocatalysts in the C-C and C-heteroatom bond forming cascade reactions for the synthesis of biologically active heterocyclic scaffolds
    Perez Mayoral, E.
    Soriano, E.
    Calvino-Casilda, V.
    Rojas-Cervantes, M. L.
    Martin-Aranda, R. M.
    CATALYSIS TODAY, 2017, 285 : 65 - 88
  • [23] Natural food additives as green catalysts in organic synthesis: a review
    Ahmad Ruslan, Nur Aimi Aqilah
    Kan, Su-Yin
    Hamzah, Ahmad Sazali
    Chia, Poh Wai
    ENVIRONMENTAL CHEMISTRY LETTERS, 2021, 19 (04) : 3359 - 3380
  • [24] An approach towards the synthesis of novel fused nitrogen tricyclic heterocyclic scaffolds via GBB reaction
    Balwe, Sandip Gangadhar
    Jeong, Yeon Tae
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 16 (08) : 1287 - 1296
  • [25] Catalyst-free, efficient, and green procedure for the synthesis of 5-heterocyclic substituted 6-aminouracils
    Jamaledini, Azar
    Mohammadizadeh, Mohammad Reza
    Mousavi, S. Hekmat
    MONATSHEFTE FUR CHEMIE, 2018, 149 (08): : 1421 - 1428
  • [26] Green Methods for the Synthesis of Pyrazoles: A Review
    Singh, Raman
    Kaur, Rajneesh
    Ahlawat, Priyanka
    Kaushik, Parul
    Singh, Kuldeep
    ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 2021, 53 (04) : 317 - 351
  • [27] MWCNTs-ZrO2as a reusable heterogeneous catalyst for the synthesis ofN-heterocyclic scaffolds under green reaction medium
    Halder, Bipasa
    Banerjee, Flora
    Nag, Ahindra
    APPLIED ORGANOMETALLIC CHEMISTRY, 2020, 34 (11)
  • [28] Green Synthesis of Privileged Benzimidazole Scaffolds Using Active Deep Eutectic Solvent
    Di Gioia, Maria Luisa
    Cassano, Roberta
    Costanzo, Paola
    Herrera Cano, Natividad
    Maiuolo, Loredana
    Nardi, Monica
    Nicoletta, Fiore Pasquale
    Oliverio, Manuela
    Procopio, Antonio
    MOLECULES, 2019, 24 (16):
  • [29] Bioprospecting of Nitrogenous Heterocyclic Scaffolds with Potential Action for Neglected Parasitosis: A Review
    Albino, Sonaly L.
    da Silva, Jamire M.
    Nobre, Michelangela S. de C.
    de M e Silva, Yvnni M. S.
    Santos, Mirelly B.
    de Araujo, Rodrigo S. A.
    de Lima, Maria C. A.
    Schmitt, Martine
    de Moura, Ricardo O.
    CURRENT PHARMACEUTICAL DESIGN, 2020, 26 (33) : 4112 - 4150
  • [30] Microwave Radiations: A Green Approach to the Synthesis of Five-Membered Heterocyclic Compounds
    Kamboj, Monika
    Bajpai, Sangeeta
    Yadav, Monika
    Singh, Surabhi
    CURRENT GREEN CHEMISTRY, 2023, 10 (01) : 57 - 72