Access to distal meta-C-H functionalization of arylmethanesulfonic acid derivatives

被引：6

作者：

Srinivas, Dasari ^{[1
]}

Mounika, Kurella ^{[1
]}

Satyanarayana, Gedu ^{[1
]}

机构：

[1] Indian Inst Technol IIT, Dept Chem, Sangareddy 502284, India

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 59期

关键词：

OLEFINATION; TEMPLATE; ACETOXYLATION; ALKENYLATION; BONDS;

D O I：

10.1039/d3cc02260a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, we report the meta-C-H olefination of arylmethanesulfonates aided by a potentially versatile aliphatic nitrile-directing group under microwave irradiation conditions with fair to very good yields and good to outstanding regioselectivities. Significantly, the protocol showed broad substrate scope including olefin-derived drugs and cyclic olefins. Remarkably, a dual meta-C-H bond was amenable to generating the bis-olefination products.

引用

页码：9106 / 9109

页数：4

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