Internal exposure risk based on urinary metabolites of PAHs of occupation and non-occupation populations around a non-ferrous metal smelting plant

被引:14
作者
Wu, Bizhi [1 ,2 ]
Lin, Meiqing [1 ,2 ]
Li, Hailing [1 ,2 ]
Wu, Yingjun [1 ,2 ]
Qi, Mengdie [1 ,2 ]
Tang, Jian [1 ,2 ]
Ma, Shengtao [1 ,2 ]
Li, Guiying [1 ,2 ]
An, Taicheng [1 ,2 ]
机构
[1] Guangdong Univ Technol, Guangdong Hong Kong Macao Joint Lab Contaminants, Guangdong Key Lab Environm Catalysis & Hlth Risk C, Inst Environm Hlth & Pollut Control, Guangzhou 510006, Peoples R China
[2] Guangdong Univ Technol, Guangzhou Key Lab Environm Catalysis & Pollut Cont, Key Lab City Cluster Environm Safety & Green Dev, Sch Environm Sci & Engn,Minist Educ, Guangzhou 510006, Peoples R China
基金
中国国家自然科学基金;
关键词
Non-ferrous metal smelting; Monohydroxylated polycyclic aromatic; hydrocarbons; Human biomonitoring; Urinary metabolites; Health risks; POLYCYCLIC AROMATIC-HYDROCARBONS; OXIDATIVE STRESS; CANCER-RISK; HEALTH; 1-HYDROXYPYRENE; ASSOCIATIONS; BIOMARKERS; EXCRETION; SAMPLE; AREA;
D O I
10.1016/j.jhazmat.2023.131563
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The emission of various metals from non-ferrous metal smelting activities is well known. However, relative investigations on potential occupational exposure of organic pollutants are still limited. Herein, total of 619 human urine samples were collected from workers engaged in smelting activities and residents living near and/or far from the smelting sites, and ten mono-hydroxylated metabolites of polycyclic aromatic hydrocarbons (OHPAHs) in human urine were determined. The median levels of sigma 10OH-PAHs in smelting workers (25.6 ng/mL) were significantly higher (p < 0.01) than that of surrounding residents (9.00 ng/mL) and rural residents as the control (8.17 ng/mL), indicating an increase in occupational PAH exposure in non-ferrous metal smelting activities. The composition profiles of OH-PAH congeners were similar in three groups, in which naphthalene metabolites accounted for 76-82% of the total. The effects of smoking, drinking, gender, BMI, and occupational categories on urinary OH-PAHs were considered. The partial correlation analysis showed an insignificant effect of non-ferrous metal smelting activities on PAH exposure for surrounding residents. In the health risk assessments, almost all smelting workers had cancer risks exceeded the acceptable level of 10-6. This study provides a reference to occupational PAH exposure and reinforce the necessary of health monitoring among smelting workers.
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页数:8
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共 55 条
  • [1] Polycyclic aromatic hydrocarbon exposure and pediatric asthma in children: a case-control study
    Al-Daghri, Nasser M.
    Alokail, Majed S.
    Abd-Alrahman, Sherif H.
    Draz, Hossam M.
    Yakout, Sobhy M.
    Clerici, Mario
    [J]. ENVIRONMENTAL HEALTH, 2013, 12
  • [2] Alagic S., 2017, ENVIRON SCI POLLUT R
  • [3] Development of sample extraction and clean-up strategies for target and non-target analysis of environmental contaminants in biological matrices
    Baduel, Christine
    Mueller, Jochen F.
    Tsai, Henghang
    Ramos, Maria Jose Gomez
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2015, 1426 : 33 - 47
  • [4] Carcinogenic polycyclic aromatic hydrocarbon-DNA adducts and mechanism of action
    Baird, WM
    Hooven, LA
    Mahadevan, B
    [J]. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2005, 45 (2-3) : 106 - 114
  • [5] Polycyclic aromatic hydrocarbons (PAHs) in soils of an industrial area in semi-arid Uzbekistan: spatial distribution, relationship with trace metals and risk assessment
    Bandowe, Benjamin A. Musa
    Shukurov, Nosir
    Leimer, Sophia
    Kersten, Michael
    Steinberger, Yosef
    Wilcke, Wolfgang
    [J]. ENVIRONMENTAL GEOCHEMISTRY AND HEALTH, 2021, 43 (11) : 4847 - 4861
  • [6] Urinary polycyclic aromatic hydrocarbon metabolites levels in a representative sample of the Spanish adult population: The BIOAMBIENT.ES project
    Bartolome, Monica
    Ramos, Juan Jose
    Cutanda, Francisco
    Huetos, Olga
    Esteban, Marta
    Ruiz-Moraga, Montserrat
    Calvo, Eva
    Perez-Gomez, Beatriz
    Gonzalez, Oscar
    Castano, Argelia
    [J]. CHEMOSPHERE, 2015, 135 : 436 - 446
  • [7] Occurrence and distribution of OCPs and PAHs in water, soil and sediment of Daye lake
    Bhutto, Seerat Ul Ain
    Xing, Xinli
    Shi, Mingming
    Mao, Yao
    Hu, Tianpeng
    Tian, Qian
    Cheng, Cheng
    Liu, Weijie
    Chen, Zhanle
    Qi, Shihua
    [J]. JOURNAL OF GEOCHEMICAL EXPLORATION, 2021, 226 (226)
  • [8] Oxidative stress and respiratory symptoms due to human exposure to polycyclic aromatic hydrocarbons (PAHs) in Kumasi, Ghana
    Bortey-Sam, Nesta
    Ikenaka, Yoshinori
    Akoto, Osei
    Nakayama, Shouta M. M.
    Asante, Kwadwo A.
    Baidoo, Elvis
    Obirikorang, Christian
    Saengtienchai, Aksorn
    Isoda, Norikazu
    Nimako, Collins
    Mizukawa, Hazuki
    Ishizuka, Mayumi
    [J]. ENVIRONMENTAL POLLUTION, 2017, 228 : 311 - 320
  • [9] Urinary profiles to assess polycyclic aromatic hydrocarbons exposure in coke-oven workers
    Campo, Laura
    Rossella, Federica
    Pavanello, Sofia
    Mielzynska, Danuta
    Siwinska, Ewa
    Kapka, Lucyna
    Bertazzi, Pier Alberto
    Fustinoni, Silvia
    [J]. TOXICOLOGY LETTERS, 2010, 192 (01) : 72 - 78
  • [10] Effects of environmental and lifestyle exposures on urinary levels of polycyclic aromatic hydrocarbon metabolites: A cross-sectional study of urban adults in China
    Cao, Limin
    Wang, Dongming
    Wen, Yuhan
    He, Heng
    Chen, Ailian
    Hu, Dan
    Tan, Aijun
    Shi, Tingming
    Zhu, Kejing
    Ma, Jixuan
    Zhou, Yun
    Chen, Weihong
    [J]. CHEMOSPHERE, 2020, 240