Diagnostic value of visceral adiposity index in chronic kidney disease: a meta-analysis

被引:9
作者
Fang, Tingting [1 ]
Zhang, Qiuling [2 ]
Wang, Yanmei [3 ]
Zha, Hui [4 ]
机构
[1] Hangzhou Normal Univ, Sch Publ Hlth, Hangzhou 311121, Zhejiang, Peoples R China
[2] Affiliated Hosp Hangzhou Normal Univ, Dept Endocrinol, Hangzhou 311121, Zhejiang, Peoples R China
[3] Gongli Hosp Shanghai Pudong New Area, Pudong New Area, Shanghai 200120, Peoples R China
[4] Affiliated Nanjing Med Univ, Lianshui Peoples Hosp Kangda Coll, Dept Blood Transfus, Huaian 223400, Jiangsu, Peoples R China
关键词
Meta-analysis; Visceral adiposity index (VAI); Chronic kidney disease (CKD); ENDOPLASMIC-RETICULUM STRESS; OBESITY; TISSUE; RISK;
D O I
10.1007/s00592-023-02048-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
AimsSeveral studies have revealed inconsistencies about the predictive properties of visceral adiposity index (VAI) in identifying chronic kidney disease (CKD). To date, it is unclear whether the VAI is a valuable diagnostic tool for CKD. This study intended to evaluate the predictive properties of the VAI in identifying CKD.MethodsThe PubMed, Embase, Web of Science, and Cochrane databases were searched for all studies that met our criteria from the earliest available article until November 2022. Articles were assessed for quality using the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). The heterogeneity was explored with the Cochran Q test and I-2 test. Publication bias was detected using Deek's Funnel plot. Review Manager 5.3, Meta-disc 1.4, and STATA 15.0 were used for our study.ResultsSeven studies involving 65,504 participants met our selection criteria and were therefore included in the analysis. Pooled sensitivity (Sen), specificity (Spe), positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR) and area under the curve (AUC) were 0.67 (95%CI: 0.54-0.77), 0.75 (95%CI: 0.65-0.83), 2.7 (95%CI: 1.7-4.2), 0.44 (95%CI: 0.29-0.66), 6 (95%CI:3.00-14.00) and 0.77 (95%CI: 0.74-0.81), respectively. Subgroup analysis indicated that mean age of subjects was the potential source of heterogeneity. The Fagan diagram found that the predictive properties of CKD were 73% when the pretest probability was set to 50%.ConclusionsThe VAI is a valuable agent in predicting CKD and may be helpful in the detection of CKD. More studies are needed for further validation.
引用
收藏
页码:739 / 748
页数:10
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