Carbon-based nanozymes: Design, catalytic mechanism, and bioapplication

被引:156
作者
Sun, Yun [1 ]
Xu, Bolong [1 ]
Pan, Xueting [1 ]
Wang, Hongyu [1 ]
Wu, Qingyuan [1 ]
Li, Shanshan [1 ]
Jiang, Bingyin [2 ]
Liu, Huiyu [1 ]
机构
[1] Beijing Univ Chem Technol, Beijing Adv Innovat Ctr Soft Matter Sci & Engn, State Key Lab Organ Inorgan Composites, Beijing Lab Biomed Mat,Bionanomaterials & Translat, Beijing 100029, Peoples R China
[2] Capital Med Univ, Sch Pharmaceut Sci, Beijing Area Major Lab Peptide & Small Mol Drugs, Beijing 100069, Peoples R China
基金
中国国家自然科学基金;
关键词
Carbon -based nanozymes; Reactive oxygen species; Catalytic therapy; Synergistic therapy; PEROXIDASE-LIKE ACTIVITY; SINGLE-ATOM NANOZYMES; COLORIMETRIC DETECTION; DOPED GRAPHENE; PH RANGE; DOTS; NANOMATERIALS; SUPEROXIDE; NANOTUBES; OXIDASE;
D O I
10.1016/j.ccr.2022.214896
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Carbon-based nanomaterials with enzyme-like activity are new candidates in materials science. So far, various carbon-based nanozymes have been developed, such as fullerenes, graphene quantum dots and metal organic framework-derived carbon materials. Unlike natural enzymes, carbon-based nano-zymes have abundant active sites, excellent stability, and good biological safety, showing great potential in biomedical applications. In particular, the unique optical, thermal and acoustic properties of carbon -based nanozymes have also been revealed, providing a multifunctional platform for its biomedical appli-cations. This review discusses the recent research progress of carbon-based nanozymes and proposes their current challenges and perspectives.(c) 2022 Elsevier B.V. All rights reserved.
引用
收藏
页数:23
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