Iodosulfonylation of [1.1.1]Propellane

被引：0

作者：

Chen, Mengke ^{[1
]}

Ling, Min ^{[1
]}

Huang, Zhiwei ^{[1
]}

Cheng, Dongping ^{[1
]}

Li, Jing-Hua ^{[1
]}

机构：

[1] Zhejiang Univ Technol, Coll Pharmaceut Sci, Hangzhou 310014, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2024年 / 56卷 / 15期

基金：

中国国家自然科学基金;

关键词：

1.1.1]propellane; bicyclo[1.1.1]pentane; sulfonyl hydrazides; iodosulfonylation; radical reaction; SULFONYL HYDRAZIDES;

D O I：

10.1055/a-2290-6540

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient disubstituted functionalization of [1.1.1] propellane has been developed. The protocol utilizes sulfonyl hydrazides and N-iodosuccinimide, enabling the introduction of iodine and sulfonyl groups into bicyclo[1.1.1]pentane (BCP) in moderate to excellent yields. It has the advantages of simple operation, mild conditions, and broad substrate scope.

引用

页码：2379 / 2384

页数：6

共 10 条

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[3] Iodosulfonylation of Alkynes under Ultrasound Irradiation
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[4] KI as iodine source for the synthesis of E-iodovinyl sulfones via metal-free iodosulfonylation of terminal alkynes
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[6] Selective halocyclization and iodosulfonylation of N-benzothiazol-2-yl alkynamides under mild conditions
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[7] Iodine promoted iodosulfonylation of alkynes with sulfonyl hydrazides in an aqueous medium: highly stereoselective synthesis of (E)-β-iodo vinylsulfones
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[8] Synthesis of (E)-β-iodo vinylsulfones via iodine-promoted iodosulfonylation of alkynes with sodium sulfinates in an aqueous medium at room temperature
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[9] Unveiling the Synthetic Potential of Substituted Phenols as Fully Recyclable Organophotoredox Catalysts for the Iodosulfonylation of Olefins
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[10] I2O5 Promoted Iodosulfonylation of Alkynes with Sulfonylhydrazides to Synthesis (E)-β-Iodovinyl Sulfones under Peroxide-Free Conditions
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