MicroRNA electrochemical biosensors for pancreatic cancer

被引：6

作者：

Rahdan, Fereshteh ^{[1
]}

Bina, Fateme ^{[2
]}

Dolatabadi, Elham Norouz ^{[1
]}

Shaterabadi, Donya ^{[2
]}

Khatami, Seyyed Hossein ^{[3
]}

Karami, Yousof ^{[4
]}

Dorosti, Nafiseh ^{[5
]}

Taheri-Anganeh, Mortaza ^{[6
]}

Asadi, Peyman ^{[7
]}

Soltani, Rahmatollah ^{[8
,9
]}

Pashaei, Mohammad Reza ^{[10
]}

Movahedpour, Ahmad ^{[11
]}

机构：

[1] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Biotechnol, Tabriz, Iran

[2] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Nanotechnol, Tabriz, Iran

[3] Shahid Beheshti Univ Med Sci, Sch Med, Dept Clin Biochem, Tehran, Iran

[4] Shahid Bahonar Univ Kerman, Fac Vet Med, Dept Clin Sci, Kerman, Iran

[5] Shahid Beheshti Univ Med Sci, Sch Adv Technol Med, Dept Med Nanotechnol, Tehran, Iran

[6] Urmia Univ Med Sci, Cellular & Mol Med Res Inst, Cellular & Mol Res Ctr, Orumiyeh, Iran

[7] Mazandaran Univ Med Sci, Fac Adv Technol Med, Dept Med Nanotechnol, Sari, Iran

[8] Shiraz Univ Med Sci, Clin Educ Res Ctr, Sch Med, Shiraz, Iran

[9] Shiraz Univ Med Sci, Student Res Comm, Shiraz, Iran

[10] Urmia Univ Med Sci, Sch Med, Dept Internal Med, Orumiyeh, Iran

[11] Behbahan Fac Med Sci, Behbahan, Iran

来源：

CLINICA CHIMICA ACTA | 2023年 / 548卷

关键词：

Pancreatic cancer; MicroRNA; Biosensor; Diagnosis; STRAND DISPLACEMENT REACTION; CELL-PROLIFERATION; MIRNAS; TRENDS; EPIDEMIOLOGY; BIOMARKERS; DIAGNOSIS; DESIGN;

D O I：

10.1016/j.cca.2023.117472

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Pancreatic cancer (PC) is one of the deadliest cancers worldwide. MicroRNAs (miRs) are sensitive molecular diagnostic tools that can serve as highly accurate biomarkers in many disease states in general and cancer specifically. MiR-based electrochemical biosensors can be easily and inexpensively manufactured, making them suitable for clinical use and mass production for point-of-care use. This paper reviews nanomaterial-enhanced miR-based electrochemical biosensors in pancreatic cancer detection, analyzing both labeled and label-free approaches, as well as enzyme-based and enzyme-free methods.

引用

页数：6

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