Liquid Biopsies in Breast Milk for the Early Detection of Breast Cancer

被引：1
作者：
Cunningham, Niamh [1 ,2 ,3 ]
Turner, Nicholas C. [1 ,2 ,3 ,4 ,5 ]
机构：
[1] Inst Canc Res, Breast Canc Now Res Ctr, London, England
[2] Royal Marsden Hosp NHS Fdn Trust, Ralph Lauren Ctr Breast Canc Res, London, England
[3] Royal Marsden Hosp NHS Fdn Trust, Breast Unit, London, England
[4] Inst Canc Res, 237 Fulham Rd, London SW3 6JB, England
[5] Royal Marsden Hosp, 237 Fulham Rd, London SW3 6JB, England
来源：
CANCER DISCOVERY | 2023年 / 13卷 / 10期
关键词：
PREGNANCY; DEFINITION;
D O I：
10.1158/2159-8290.CD-23-0836
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Cell-free tumor DNA has previously been detected in nonblood sources, including urine, saliva, stool, cerebrospinal fluid, and pleural fluid. In this issue, Saura and colleagues present a novel proof-of-concept study demonstrating that detection of tumor DNA in breast milk is feasible and may be a potential future strategy to screen for postpartum breast cancer. See related article by Saura et al., p. 2180 (14). Summary: Cell-free tumor DNA has previously been detected in nonblood sources, including urine, saliva, stool, cerebrospinal fluid, and pleural fluid. In this issue, Saura and colleagues present a novel proof-of-concept study demonstrating that detection of tumor DNA in breast milk is feasible and may be a potential future strategy to screen for postpartum breast cancer.
引用
收藏
页码：2125 / 2127
页数：3
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共 14 条
  • [11] Potential of Using Cell-Free DNA and miRNA in Breast Milk to Screen Early Breast Cancer
    Song, Qinghe
    Zhang, Yingying
    Liu, Hongtao
    Du, Yuguang
    [J]. BIOMED RESEARCH INTERNATIONAL, 2020, 2020
  • [12] Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy
    Springer, Simeon U.
    Chen, Chung-Hsin
    Pena, Maria Del Carmen Rodriguez
    Li, Lu
    Douville, Christopher
    Wang, Yuxuan
    Cohen, Joshua David
    Taheri, Diana
    Silliman, Natalie
    Schaefer, Joy
    Ptak, Janine
    Dobbyn, Lisa
    Papoli, Maria
    Kinde, Isaac
    Afsari, Bahman
    Tregnago, Aline C.
    Bezerra, Stephania M.
    VandenBussche, Christopher
    Fujita, Kazutoshi
    Ertoy, Dilek
    Cunha, Isabela W.
    Yu, Lijia
    Bivalacqua, Trinity J.
    Grollman, Arthur P.
    Diaz, Luis A.
    Karchin, Rachel
    Danilova, Ludmila
    Huang, Chao-Yuan
    Shun, Chia-Tung
    Turesky, Robert J.
    Yun, Byeong Hwa
    Rosenquist, Thomas A.
    Pu, Yeong-Shiau
    Hruban, Ralph H.
    Tomasetti, Cristian
    Papadopoulos, Nickolas
    Kinzler, Ken W.
    Vogelstein, Bert
    Dickman, Kathleen G.
    Netto, George J.
    [J]. ELIFE, 2018, 7
  • [13] Circulating tumour DNA - looking beyond the blood
    Tivey, Ann
    Church, Matt
    Rothwell, Dominic
    Dive, Caroline
    Cook, Natalie
    [J]. NATURE REVIEWS CLINICAL ONCOLOGY, 2022, 19 (09) : 600 - 612
  • [14] Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas
    Wang, Yuxuan
    Springer, Simeon
    Mulvey, Carolyn L.
    Silliman, Natalie
    Schaefer, Joy
    Sausen, Mark
    James, Nathan
    Rettig, Eleni M.
    Guo, Theresa
    Pickering, Curtis R.
    Bishop, Justin A.
    Chung, Christine H.
    Califano, Joseph A.
    Eisele, David W.
    Fakhry, Carole
    Gourin, Christine G.
    Ha, Patrick K.
    Kang, Hyunseok
    Kiess, Ana
    Koch, Wayne M.
    Myers, Jeffrey N.
    Quon, Harry
    Richmon, Jeremy D.
    Sidransky, David
    Tufano, Ralph P.
    Westra, William H.
    Bettegowda, Chetan
    Diaz, Luis A., Jr.
    Papadopoulos, Nickolas
    Kinzler, Kenneth W.
    Vogelstein, Bert
    Agrawal, Nishant
    [J]. SCIENCE TRANSLATIONAL MEDICINE, 2015, 7 (293)
12