Liquid Biopsies in Breast Milk for the Early Detection of Breast Cancer

被引：1
作者：
Cunningham, Niamh [1 ,2 ,3 ]
Turner, Nicholas C. [1 ,2 ,3 ,4 ,5 ]
机构：
[1] Inst Canc Res, Breast Canc Now Res Ctr, London, England
[2] Royal Marsden Hosp NHS Fdn Trust, Ralph Lauren Ctr Breast Canc Res, London, England
[3] Royal Marsden Hosp NHS Fdn Trust, Breast Unit, London, England
[4] Inst Canc Res, 237 Fulham Rd, London SW3 6JB, England
[5] Royal Marsden Hosp, 237 Fulham Rd, London SW3 6JB, England
来源：
CANCER DISCOVERY | 2023年 / 13卷 / 10期
关键词：
PREGNANCY; DEFINITION;
D O I：
10.1158/2159-8290.CD-23-0836
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Cell-free tumor DNA has previously been detected in nonblood sources, including urine, saliva, stool, cerebrospinal fluid, and pleural fluid. In this issue, Saura and colleagues present a novel proof-of-concept study demonstrating that detection of tumor DNA in breast milk is feasible and may be a potential future strategy to screen for postpartum breast cancer. See related article by Saura et al., p. 2180 (14). Summary: Cell-free tumor DNA has previously been detected in nonblood sources, including urine, saliva, stool, cerebrospinal fluid, and pleural fluid. In this issue, Saura and colleagues present a novel proof-of-concept study demonstrating that detection of tumor DNA in breast milk is feasible and may be a potential future strategy to screen for postpartum breast cancer.
引用
收藏
页码：2125 / 2127
页数：3
相关论文
共 14 条
  • [1] Outcome of breast cancer patients treated with chemotherapy during pregnancy compared with non-pregnant controls
    Amant, Frederic
    Nekljudova, Valentina
    Maggen, Charlotte
    Seither, Fenja
    Neven, Patrick
    Cardonick, Elyce H.
    Schmatloch, Sabine
    Van Calsteren, Kristel
    Cordes, Tatjana
    de Haan, Jorine
    Lok, Christianne A. R.
    Flock, Felix
    Boere, Ingrid A.
    Gziri, Mina M.
    Solbach, Christine
    Lefrere, Hanne
    Schneeweiss, Andreas
    Witzel, Isabell
    Seiler, Sabine
    Loibl, Sibylle
    [J]. EUROPEAN JOURNAL OF CANCER, 2022, 170 : 54 - 63
  • [2] Amant F, 2021, LANCET ONCOL, V22, P753, DOI [10.1016/S1470-2045(21)00183-2, 10.1016/s1470-2045(21)00183-2]
  • [3] Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-associated breast cancer
    Callihan, Eryn B.
    Gao, Dexiang
    Jindal, Sonali
    Lyons, Traci R.
    Manthey, Elizabeth
    Edgerton, Susan
    Urquhart, Alexander
    Schedin, Pepper
    Borges, Virginia F.
    [J]. BREAST CANCER RESEARCH AND TREATMENT, 2013, 138 (02) : 549 - 559
  • [4] Association Between Postpartum Breast Cancer Diagnosis and Metastasis and the Clinical Features Underlying Risk
    Goddard, Erica T.
    Bassale, Solange
    Schedin, Troy
    Jindal, Sonali
    Johnston, Jeremy
    Cabral, Ethan
    Latour, Emile
    Lyons, Traci R.
    Mori, Motomi
    Schedin, Pepper J.
    Borges, Virginia F.
    [J]. JAMA NETWORK OPEN, 2019, 2 (01)
  • [5] Breast Cancer Diagnosed During Pregnancy Adapting Recent Advances in Breast Cancer Care for Pregnant Patients
    Loibl, Sibylle
    Schmidt, Andre
    Gentilini, Oreste
    Kaufman, Bella
    Kuhl, Christine
    Denkert, Carsten
    von Minckwitz, Gunter
    Parokonnaya, Anastasia
    Stensheim, Hanne
    Thomssen, Christoph
    van Calsteren, Kristel
    Poortmans, Philip
    Berveiller, Paul
    Markert, Udo R.
    Amant, Frederic
    [J]. JAMA ONCOLOGY, 2015, 1 (08) : 1145 - 1153
  • [6] Pregnancy and Breast Cancer: when They Collide
    Lyons, Traci R.
    Schedin, Pepper J.
    Borges, Virginia F.
    [J]. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 2009, 14 (02) : 87 - 98
  • [7] Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes
    Nuzzo, Pier Vitale
    Berchuck, Jacob E.
    Korthauer, Keegan
    Spisak, Sandor
    Nassar, Amin H.
    Abou Alaiwi, Sarah
    Chakravarthy, Ankur
    Shen, Shu Yi
    Bakouny, Ziad
    Boccardo, Francesco
    Steinharter, John
    Bouchard, Gabrielle
    Curran, Catherine R.
    Pan, Wenting
    Baca, Sylvan C.
    Seo, Ji-Heui
    Lee, Gwo-Shu Mary
    Michaelson, M. Dror
    Chang, Steven L.
    Waikar, Sushrut S.
    Sonpavde, Guru
    Irizarry, Rafael A.
    Pomerantz, Mark
    De Carvalho, Daniel D.
    Choueiri, Toni K.
    Freedman, Matthew L.
    [J]. NATURE MEDICINE, 2020, 26 (07) : 1041 - +
  • [8] Prediagnostic breast milk DNA methylation alterations in women who develop breast cancer
    Salas, Lucas A.
    Lundgren, Sara N.
    Browne, Eva P.
    Punska, Elizabeth C.
    Anderton, Douglas L.
    Karagas, Margaret R.
    Arcaro, Kathleen F.
    Christensen, Brock C.
    [J]. HUMAN MOLECULAR GENETICS, 2020, 29 (04) : 662 - 673
  • [9] Early-Stage Breast Cancer Detection in Breast Milk
    Saura, Cristina
    Ortiz, Carolina
    Matito, Judit
    Arenas, Enrique J.
    Sunol, Anna
    Martin, Agatha
    Cordoba, Octavi
    Martinez-Sabadell, Alex
    Garcia-Ruiz, Itziar
    Miranda, Ignacio
    Morales-Comas, Clara
    Carrasco, Estela
    Viaplana, Cristina
    Peg, Vicente
    Nuciforo, Paolo
    Bayo-Puxan, Neus
    Gonzalez-Medina, Alberto
    Miquel, Josep M.
    Gomez-Rey, Marina
    Villacampa, Guillermo
    Arevalo, Silvia
    Espinosa-Bravo, Martin
    Balmana, Judith
    Dienstmann, Rodrigo
    Arribas, Joaquin
    Tabernero, Josep
    Vivancos, Ana
    Sanso, Miriam
    [J]. CANCER DISCOVERY, 2023, 13 (10) : 2180 - 2191
  • [10] Original Research Overall survival is the lowest among young women with postpartum breast cancer
    Shagisultanova, Elena
    Gao, Dexiang
    Callihan, Eryn
    Parris, Hannah J.
    Risendal, Betsy
    Hines, Lisa M.
    Slattery, Martha L.
    Baumgartner, Kathy
    Schedin, Pepper
    John, Esther M.
    Borges, Virginia F.
    [J]. EUROPEAN JOURNAL OF CANCER, 2022, 168 : 119 - 127
12