Corpus callosum involvement in MOG antibody-associated disease in comparison to AQP4-IgG-seropositive neuromyelitis optica spectrum disorder and multiple sclerosis

被引：11

作者：

Chia, Nicholas H. ^{[1
]}

Redenbaugh, Vyanka ^{[1
]}

Chen, John J. ^{[1
]}

Pittock, Sean J. ^{[1
,2
]}

Flanagan, Eoin P. ^{[1
,2
]}

机构：

[1] Mayo Clin, Dept Neurol, 200 First St SW, Rochester, MN 55905 USA

[2] Mayo Clin, Dept Lab Med & Pathol, 200 First St SW, Rochester, MN 55905 USA

来源：

MULTIPLE SCLEROSIS JOURNAL | 2023年 / 29卷 / 06期

关键词：

Myelin oligodendrocyte glycoprotein; corpus callosum; magnetic resonance imaging; multiple sclerosis; aquaporin; 4; neuromyelitis optica;

D O I：

10.1177/13524585221150743

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: Data on corpus callosum involvement in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are limited. Objective: The objective of the study was to compare callosal lesions in MOGAD, multiple sclerosis (MS), and aquaporin-4-IgG positive neuromyelitis optica spectrum disorder (AQP4+NMOSD). Results: Callosal lesion frequency was similar in MOGAD (38/171 (22%)), MS (24/72 (33%)), and AQP4+NMOSD (18/63 (29%)). Clinical phenotypes included encephalopathy (47%) and focal supratentorial (21%) or infratentorial (45%) deficits. None had callosal-disconnection syndromes. Maximal callosal-T2-lesion diameter (median (range)) in millimeter was similar in MOGAD (21 (4-77)) and AQP4+NMOSD (22 (5-49); p = 0.93) but greater than in MS (10.5 (2-64)). Extracallosal extension (21/38 (55%)) and T2-lesion resolution (19/34 (56%)) favored MOGAD. Conclusions: Despite similar frequency and imaging overlap, larger lesions, sagittal midline involvement, and lesion resolution favored MOGAD.

引用

页码：748 / 752

页数：5

共 10 条

[1] Callosal lesions on magnetic resonance imaging with multiple sclerosis, neuromyelitis optica spectrum disorder and acute disseminated encephalomyelitis [J].

Cai, Meng-Ting ;

Zhang, Yin-Xi ;

Zheng, Yang ;

Fang, Wei ;

Ding, Mei-Ping .

MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2019, 32 :41-45

[2] Different magnetic resonance imaging features between MOG antibody- and AQP4 antibody-mediated disease: A Chinese cohort study [J].

Chen, Chen ;

Liu, Chunxin ;

Fang, Ling ;

Zou, Yan ;

Ruan, Hengfang ;

Wang, Yuge ;

Cui, Chunping ;

Sun, Xiaobo ;

Peng, Lisheng ;

Qiu, Wei .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 2019, 405

[3] Clinical and Radiological Features of Adult Onset Bilateral Medial Frontal Cerebral Cortical Encephalitis With Anti-myelin Oligodendrocyte Glycoprotein Antibody [J].

Fujimori, Juichi ;

Nakamura, Masashi ;

Yagihashi, Takahito ;

Nakashima, Ichiro .

FRONTIERS IN NEUROLOGY, 2020, 11

[4] The corpus callosum in the diagnosis of multiple sclerosis and other CNS demyelinating and inflammatory diseases [J].

Garg, Nidhi ;

Reddel, Stephen W. ;

Miller, David H. ;

Chataway, Jeremy ;

Riminton, D. Sean ;

Barnett, Yael ;

Masters, Lynette ;

Barnett, Michael H. ;

Hardy, Todd A. .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2015, 86 (12) :1374-1382

[5] Distinct brain imaging characteristics of autoantibody-mediated CNS conditions and multiple sclerosis [J].

Jurynczyk, Maciej ;

Geraldes, Ruth ;

Probert, Fay ;

Woodhall, Mark R. ;

Waters, Patrick ;

Tackley, George ;

DeLuca, Gabriele ;

Chandratre, Saleel ;

Leite, Maria I. ;

Vincent, Angela ;

Palace, Jacqueline .

BRAIN, 2017, 140 :617-627

[6] Myelin-oligodendrocyte glycoprotein antibody-associated disease [J].

Marignier, Romain ;

Hacohen, Yael ;

Cobo-Calvo, Alvaro ;

Probstel, Anne-Katrin ;

Aktas, Orhan ;

Alexopoulos, Harry ;

Amato, Maria-Pia ;

Asgari, Nasrin ;

Banwell, Brenda ;

Bennett, Jeffrey ;

Brilot, Fabienne ;

Capobianco, Marco ;

Chitnis, Tanuja ;

Ciccarelli, Olga ;

Deiva, Kumaran ;

De Seze, Jerome ;

Fujihara, Kazuo ;

Jacob, Anu ;

Kim, Ho Jin ;

Kleiter, Ingo ;

Lassmann, Hans ;

Leite, Maria-Isabel ;

Linington, Christopher ;

Meinl, Edgar ;

Palace, Jacqueline ;

Paul, Friedemann ;

Petzold, Axel ;

Pittock, Sean ;

Reindl, Markus ;

Sato, Douglas Kazutoshi ;

Selmaj, Krzysztof ;

Siva, Aksel ;

Stankoff, Bruno ;

Tintore, Mar ;

Traboulsee, Anthony ;

Waters, Patrick ;

Waubant, Emmanuelle ;

Weinshenker, Brian ;

Derfuss, Tobias ;

Vukusic, Sandra ;

Hemmer, Bernhard .

LANCET NEUROLOGY, 2021, 20 (09) :762-772

[7] Occurrence of acute large and edematous callosal lesions in neuromyelitis optica [J].

Nakamura, M. ;

Misu, T. ;

Fujihara, K. ;

Miyazawa, I. ;

Nakashima, I. ;

Takahashi, T. ;

Watanabe, S. ;

Itoyama, Y. .

MULTIPLE SCLEROSIS, 2009, 15 (06) :695-700

[8] Comparison of MRI Lesion Evolution in Different Central Nervous System Demyelinating Disorders [J].

Sechi, Elia ;

Krecke, Karl N. ;

Messina, Steven A. ;

Buciuc, Marina ;

Pittock, Sean J. ;

Chen, John J. ;

Weinshenker, Brian G. ;

Lopez-Chiriboga, A. Sebastian ;

Lucchinetti, Claudia F. ;

Zalewski, Nicholas L. ;

Tillema, Jan Mendelt ;

Kunchok, Amy ;

Monaco, Salvatore ;

Morris, Padraig P. ;

Fryer, James P. ;

Nguyen, Adam ;

Greenwood, Tammy ;

Syc-Mazurek, Stephanie B. ;

Keegan, B. Mark ;

Flanagan, Eoin P. .

NEUROLOGY, 2021, 97 (11) :E1097-E1109

[9] Cerebral Cortical Encephalitis in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease [J].

Valencia-Sanchez, Cristina ;

Guo, Yong ;

Krecke, Karl N. ;

Chen, John J. ;

Redenbaugh, Vyanka ;

Montalvo, Mayra ;

Elsbernd, Paul M. ;

Tillema, Jan-Mendelt ;

Lopez-Chiriboga, Sebastian ;

Budhram, Adrian ;

Sechi, Elia ;

Kunchok, Amy ;

Dubey, Divyanshu ;

Pittock, Sean J. ;

Lucchinetti, Claudia F. ;

Flanagan, Eoin P. .

ANNALS OF NEUROLOGY, 2023, 93 (02) :297-302

[10] Clinical and Imaging Features of Patients With Encephalitic Symptoms and Myelin Oligodendrocyte Glycoprotein Antibodies [J].

Wang, Jingsi ;

Qiu, Zhandong ;

Li, Dawei ;

Yang, Xixi ;

Ding, Yan ;

Gao, Lehong ;

Liu, Aihua ;

Song, Yang ;

Li, Cunjiang ;

Gao, Ran ;

Wang, Lin ;

Wu, Liyong ;

Jia, Longfei ;

Guo, Dongmei ;

Zhou, Aihong ;

Jia, Jianping ;

Huang, Liyuan ;

Qu, Miao ;

Gao, Li ;

Dong, Huiqing ;

Hao, Junwei ;

Liu, Zheng .

FRONTIERS IN IMMUNOLOGY, 2021, 12

← 1 →