Disease burden of bacteraemia with extended-spectrum beta-lactamase-producing and Enterobacterales in Korea

被引：4

作者：

Lee, C. M. ^{[1
]}

Lee, S. ^{[2
,3
]}

Kim, E. S. ^{[4
]}

Kim, H. B. ^{[4
]}

Park, W. B. ^{[1
,7
]}

Moon, S. M. ^{[4
,5
]}

Kim, Y. K. ^{[6
,10
]}

Park, K. -H. ^{[5
]}

Kwak, Y. G. ^{[8
]}

Kim, B. ^{[9
]}

Kim, Y. S.

Kim, C-J. ^{[11
]}

Gil, H-Y. ^{[12
]}

Ahn, J. ^{[13
,15
]}

Song, K-H. ^{[4
,14
]}

机构：

[1] Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[2] Pusan Natl Univ, Dept Internal Med, Sch Med, Pusan, South Korea

[3] Pusan Natl Univ Hosp, Med Res Inst, Pusan, South Korea

[4] Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Coll Med, Seongnam, South Korea

[5] Hallym Univ, Sacred Heart Hosp, Dept Internal Med, Anyang, South Korea

[6] Yonsei Univ, Wonju Coll Med, Dept Internal Med, Wonju, South Korea

[7] Chonnam Natl Univ, Med Sch, Dept Infect Dis, Gwangju, South Korea

[8] Inje Univ, Ilsan Paik Hosp, Dept Internal Med, Goyang, South Korea

[9] Hanyang Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[10] Chungnam Natl Univ, Div Infect Dis, Sch Med, Daejeon, South Korea

[11] Ewha Womans Univ, Coll Med, Dept Internal Med, Seoul, South Korea

[12] Pfizer Pharmaceut Korea Ltd, Real World Evidence Team, Seoul, South Korea

[13] Ewha Womans Univ, Dept Hlth Convergence, Seoul, South Korea

[14] Seoul Natl Univ, Dept Internal Med, Bundang Hosp, 82,Gumi ro 173 Beon gil, Seongnam 13620, Gyeonggi Do, South Korea

[15] Ewha Womans Univ, Dept Hlth Convergence, 52 Ewhayeodae Gil, Seoul 03760, South Korea

来源：

JOURNAL OF HOSPITAL INFECTION | 2024年 / 144卷

关键词：

Bacteraemia; Extended-spectrum beta-lactamase; Carbapenem-resistant; Enterobacterales; ESCHERICHIA-COLI; RISK-FACTORS; INFECTION; OUTCOMES; IMPACT; COLONIZATION;

D O I：

10.1016/j.jhin.2023.11.013

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background: Despite the significant impact of multi-drug-resistant bacteraemia, especially extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) and carbapenem-resistant Enterobacterales (CRE), the burden of disease has not been investigated thoroughly. Aim: To evaluate the clinical outcomes and socio-economic burden of ESBL-E and CRE bacteraemia nationwide in the Republic of Korea. Methods: A search was undertaken for all cases of ESBL-E and CRE bacteraemia and matched controls in 10 hospitals in the Republic of Korea over 6 months. Patients with ESBL-E or CRE bacteraemia were classified as the R group, and matched controls with antibiotic-susceptible bacteraemia and without infection were classified as the S and N groups, respectively. Patients' clinical data were collected, and the economic burden was estimated based on medical expenses, loss of productivity and total costs.

引用

页码：85 / 93

页数：9

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