1,6-Addition Reactions of Difluoroenol Silyl Ethers with Benzoquinones and Quinonediimines To Access Difluorooxymethyl and Difluoroaminomethyl Compounds

被引：3

作者：

Hong, Peng ^{[1
,2
,3
]}

Xu, Jinjing ^{[1
,2
]}

Li, Jinshan ^{[1
,2
]}

Zhu, Xiaolei ^{[1
,2
]}

Ying, Anguo ^{[3
]}

Wang, Zhiming ^{[1
,2
]}

Yang, Jianguo ^{[1
,2
]}

机构：

[1] Taizhou Univ, Adv Res Inst, Jiaojiang 318000, Zhejiang, Peoples R China

[2] Taizhou Univ, Sch Pharmaceut Sci, Jiaojiang 318000, Zhejiang, Peoples R China

[3] Qufu Normal Univ, Dept Chem & Chem Engn, Qufu 273100, Shandong, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2023年 / 365卷 / 24期

关键词：

1,6-Addition; Difluoroenol Silyl Ethers; Benzoquinones; Quinonediimines; Hexafluoroisopropanol; ENOL ETHERS; ASYMMETRIC-SYNTHESIS; EFFICIENT; QUINONES; ALCOHOLS; ANALOGS; WATER; SITE;

D O I：

10.1002/adsc.202300877

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The etherification and amination of difluoroenol silyl ethers with benzoquinones and quinonediimines were achieved by using hexafluoroisopropanol (HFIP) as the solvent. This 1,6-addition reaction could construct difluorooxymethyl and difluoroaminomethyl compounds under metal-free conditions. It is preliminarily speculated that the reaction took place through a single electron transfer (SET) process. image

引用

页码：4550 / 4555

页数：6

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