Maternal and neonatal umbilical cord serum levels of 25-hydroxy vitamin D among Sudanese women with normal pregnancy: a cross-sectional study

被引:0
作者
Ahmed, Mohamed A. [1 ]
Elmugabil, Abdelmageed [2 ]
Aleed, Ashwaq [3 ,4 ]
Al-nafeesah, Abdullah [3 ,6 ]
Adam, Ishag [5 ]
机构
[1] Univ Khartoum, Fac Med, Khartoum, Sudan
[2] El Mahdi Univ, Fac Med El Imam, Kosti, Sudan
[3] Qassim Univ, Unaizah Coll Med & Med Sci, Dept Pediat, Unaizah, Saudi Arabia
[4] Qassim Univ, Coll Med, Dept Pediat, Buraydah, Saudi Arabia
[5] Qassim Univ, Unaizah Coll Med & Med Sci, Dept Obstet & Gynecol, Unaizah, Saudi Arabia
[6] Qassim Univ, Unaizah Coll Med & Med Sci, Unaizah, Saudi Arabia
关键词
Mothers; Infant; newborn; Umbilical cord; Vitamin D deficiency; Calcitriol; D DEFICIENCY; HEALTH;
D O I
10.23736/S0393-3660.23.05029-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND: There are few published studies on the association between maternal and umbilical cord serum vitamin D concentrations in Sub-Saharan Africans. Therefore, the aim of this study was to assess the association between mothers and umbilical cord 25-hydroxyvitamin D (25-[OH)]D) levels.METHODS: A cross-sectional study was conducted at the Saad Abuelela Maternity Hospital in Khartoum, Sudan. Ninety pairs of mothers and neonates (umbilical cords) were enrolled.RESULTS: The median (interquartile range) mother's age and gestational age were 28.5 (26.0-30.0) years and 38.0 (37.5-38.2) weeks, respectively. The median (IQR) umbilical cord level of 25-(OH)D was significantly higher than the median maternal level of 25-(OH)D (30.3 [18.2-38.4] vs. 20.2 [17.5], ng/mL, P=0.011). Moreover, compared to the maternal samples, a significantly low number of umbilical cord samples had a vitamin D deficiency (<= 20; 25/90 [27.8%] vs. 42/90 [46.7%], P=0.013).CONCLUSIONS: The umbilical cord 25-(OH)D levels were positively correlated with and significantly higher than the maternal 25-(OH)D levels (r=0.401).
引用
收藏
页码:686 / 690
页数:5
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