Quantitative evaluation of the lumbar ligamentum flavum using MRI T2-mapping: Efficacy of its clinical application in patients with lumbar spinal stenosis

被引：0

作者：

Takaoka, Hiromitsu ^{[1
,8
]}

Eguchi, Yawara ^{[1
,2
]}

Koroki, Junya ^{[2
]}

Orita, Sumihisa ^{[1
,3
]}

Inage, Kazuhide ^{[1
]}

Shiga, Yasuhiro ^{[1
]}

Furuya, Takeo ^{[1
]}

Maki, Satoshi ^{[1
]}

Norimoto, Masaki ^{[1
]}

Umimura, Tomotaka ^{[1
]}

Suzuki-Narita, Miyako ^{[1
]}

Sato, Takashi ^{[1
]}

Sato, Masashi ^{[1
]}

Hozumi, Takashi ^{[1
]}

Kim, Geundong ^{[1
]}

Mizuki, Norichika ^{[1
]}

Tsuchiya, Ryuto ^{[1
]}

Otagiri, Takuma ^{[1
]}

Mukaihata, Tomohito ^{[1
]}

Hishiya, Takahisa ^{[1
]}

Nakamura, Junichi ^{[1
]}

Hagiwara, Shigeo ^{[1
]}

Iwata, Shuhei ^{[1
]}

Ataka, Hiromi ^{[4
]}

Tanno, Takaaki ^{[4
]}

Watanabe, Atsuya ^{[5
]}

Aoki, Yasuchika ^{[5
]}

Inoue, Masahiro ^{[5
]}

Koda, Masao ^{[6
]}

Takahashi, Hiroshi ^{[6
]}

Akazawa, Tsutomu ^{[7
]}

Ohtori, Seiji ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Med, Dept Orthopaed Surg, 1-8-1 Inohana,Chuo Ku, Chiba 2608670, Japan

[2] Shimoshizu Natl Hosp, Dept Orthopaed Surg, 934-5 Shikawatashi, Yotsukaido, Chiba 2840003, Japan

[3] Chiba Univ, Ctr Frontier Med Engn, 1-33 Yayoi Cho,CFME Room B201,Inage Ku, Chiba 2638522, Japan

[4] Matsudo Orthopaed Hosp, Dept Orthopaed Surg, 1-161 Asahi Cho, Matsudo, Chiba 2710043, Japan

[5] Eastern Chiba Med Ctr, Dept Orthopaed Surg, 3-6-2 Okayamadai, Togane, Chiba 2838686, Japan

[6] Univ Tsukuba, Dept Orthoped Surg, 1-1-1 Tennodai, Tsukuba, Ibaraki 3058575, Japan

[7] St Marianna Univ, Sch Med, Dept Orthopaed Surg, 2-16-1 Sugao,Miyamae Ku, Kawasaki, Kanagawa 2168511, Japan

[8] 1-8-1 Inohana,Chuo Ku, Chiba 2608670, Japan

来源：

JOURNAL OF ORTHOPAEDIC SCIENCE | 2024年 / 29卷 / 01期

关键词：

Lumbar spinal stenosis; Ligamentum flavum; Magnetic resonance imaging; T-2; mapping; CANAL STENOSIS; DURAL TEARS; HYPERTROPHY; PATHOMECHANISM; ASSOCIATION; OPERATIONS; SURGERY;

D O I：

10.1016/j.jos.2022.12.013

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Obejective: To perform a magnetic resonance imaging T2-mapping of the ligamentum flavum in healthy individuals and patients with lumbar spinal stenosis scheduled for surgery and compare the T2 relaxation times. Subjects and Methods: The T2 relaxation time of the ligamentum flavum was compared among 3 groups, healthy young individuals (H group (age< 50)), healthy middle-aged and older individuals (H group (age >= 50)), and patients with lumbar spinal stenosis (L group). Additionally, the thickness of the ligament was measured in the axial image plane, and the occupied area ratio of each fiber was measured by staining the surgically obtained ligament, and each was correlated with the T2 relaxation time. We also evaluated the adhesion of the ligamentum flavum with the dura mater during the surgery. Results: The T2 relaxation times were significantly prolonged in H group (age >= 50) and L group (P < 0.001) compared to H group (age<50). The relationship between collagen fiber and T2 relaxation times was significantly positive (r = 0.720, P < 0.001). Moreover, the relaxation times were significantly prolonged in those with adhesion of the ligamentum flavum with the dura mater (P < 0.05). The cut-off for the relaxation time was 50 ms (sensitivity: 62.50%, false positive rate: 10.8%). Conclusion: Healthy middle-aged and older individuals and patients with lumbar spinal stenosis and adhesion of the ligamentum flavum with the dura mater have prolonged T2 relaxation times. Hence, the

引用

页码：101 / 108

页数：8

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