Inflammatory and Cardiovascular Correlates of Physical Activity and Sedentary Behavior in Older Adults Living With HIV

被引：3

作者：

Jones, Raymond ^{[1
,2
]}

Enogela, Ene M. ^{[1
,2
]}

Buchanan, Taylor L. ^{[1
,2
]}

Buford, Thomas W. ^{[1
,2
,3
]}

Vance, David E. ^{[4
]}

Fazeli, Pariya L. ^{[4
]}

机构：

[1] Univ Alabama Birmingham, Dept Med, Birmingham, AL 35205 USA

[2] Univ Alabama Birmingham, UAB Ctr Exercise Med, Birmingham, AL 35205 USA

[3] Birmingham VA Med Ctr, Birmingham Atlanta Geriatr Res Educ & Clin Ctr, Birmingham, AL USA

[4] Univ Alabama Birmingham, Sch Nursing, Birmingham, AL USA

来源：

JOURNAL OF PHYSICAL ACTIVITY & HEALTH | 2023年 / 20卷 / 02期

关键词：

aging; biomarkers; exercise; VIRUS-INFECTED PATIENTS; LOW-GRADE INFLAMMATION; ACTIVITY QUESTIONNAIRE; DISEASE RISK; EXERCISE; POPULATION; COAGULATION; MORTALITY; HEALTH; IPAQ;

D O I：

10.1123/jpah.2022-0304

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background: Inflammation is an indicator of oxidative stress that may contribute to cardiovascular diseases in older people living with HIV (OPWH). Physical activity (PA) may reduce these biomarkers in OPWH, but little is known about the association of PA with inflammatory and cardiovascular biomarkers. We sought to examine the inflammatory and cardiovascular biomarker correlates of PA and sedentary behavior in OPWH. Methods: We included 101 OPWH with complete assessments of PA, sedentary behavior, and biomarker data to examine the association between the volume of PA and inflammatory and cardiovascular biomarkers.Results: In this cohort of OPWH (mean age 55.9 y), 68% were male and 83% were African American/Black. Among OPWH, greater volume of PA (ie, walking, moderate, vigorous, and/or total) was associated with lower systolic (P < .05) and diastolic blood pressure (P < .05), pulse pressure (P < .05), and tumor necrosis factor-alpha (P < .05). Greater duration of sitting was associated with greater triglycerides, interleukin-6, and tumor necrosis factor-alpha (P < .05).Conclusions: Although adherence to regular PA among OPWH is low and sedentary behavior is high, the associations between biomarkers and PA suggest a greater volume of PA could attenuate the inflammatory and cardiovascular derangements experienced by OPWH.

引用

页码：149 / 156

页数：8

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