Overcoming Underpowering in the Outcome Analysis of Repaired-Tetralogy of Fallot: A Multicenter Database from the CMR/CT Working Group of the Italian Pediatric Cardiology Society (SICPed)

被引：1

作者：

Ait-Ali, Lamia ^{[1
,2
]}

Leonardi, Benedetta ^{[3
]}

Alaimo, Annalisa ^{[4
]}

Baccano, Giovanna ^{[5
]}

Bennati, Elena ^{[6
]}

Bucciarelli, Valentina ^{[7
]}

Clemente, Alberto ^{[8
]}

Favilli, Silvia ^{[6
]}

Ferroni, Francesca ^{[9
]}

Inserra, Maria Cristina ^{[10
]}

Lovato, Luigi ^{[11
]}

Maiorano, Antonella ^{[12
]}

Marcora, Simona Anna ^{[13
]}

Marrone, Chiara ^{[2
]}

Martini, Nicola ^{[2
]}

Mirizzi, Gianluca ^{[14
]}

Pasqualin, Giulia ^{[15
]}

Peritore, Giuseppe ^{[16
]}

Puppini, Giovanni ^{[17
]}

Sandrini, Camilla ^{[18
]}

Raimondi, Francesca ^{[6
,19
]}

Secchi, Francesco ^{[15
]}

Spaziani, Gaia ^{[6
]}

Stagnaro, Nicola ^{[20
]}

Salvadori, Stefano ^{[1
]}

Secinaro, Aurelio ^{[21
]}

Tchana, Bertrand ^{[22
]}

Trocchio, Gianluca ^{[23
]}

Galetti, Davide ^{[24
]}

Pieroni, Federica ^{[24
]}

Dalmiani, Stefano ^{[24
]}

Bianco, Francesco ^{[7
]}

Festa, Pierluigi ^{[2
]}

机构：

[1] Natl Res Inst, Inst Clin Physiol, I-56123 Pisa, Italy

[2] Fdn G Monasterio CNR Reg Toscana, Pediat Cardiol & GUCH Unit, Massa, Italy

[3] IRCCS, Bambino Gesu Childrens Hosp, Dept Pediat Cardiol Cardiac Surg & Heart Lung Tra, I-00100 Rome, Italy

[4] ARNAS Civ, PO G Di Cristina, UOC Cardiol Pediat, I-90123 Palermo, Italy

[5] Ctr Cardiol Pediat Mediterraneo, Dept Pediat Cardiol, I-98039 Taormina, Italy

[6] Azienda Osped Univ Meyer, Pediat Cardiol, I-50100 Florence, Italy

[7] Azienda Osped Univ Osped Riuniti Ancona Umberto I, Dept Pediat & Congenital Cardiac Surg & Cardiol, I-60123 Ancona, Italy

[8] Fdn Toscana Gabriele Monasterio, Dept Radiol, I-56123 Pisa, Italy

[9] Cardinal Massaia Hosp, Dept Radiol, I-14100 Asti, Italy

[10] Univ Hosp Vittorio Emanuele Catania, Dept Radiol, I-95100 Catania, Italy

[11] IRCCS Azienda Osped Univ Bologna, Thoracoabdominal & Emergency Radiol Unit, Pediat & Adult Cardiovasc, Via Massarenti 9, I-40138 Bologna, Italy

[12] Osped Pediat Giovanni XXIII Bari, Cardiol Pediat, Via Amendola 207, I-70100 Bari, Italy

[13] ASST Grande Osped Metropolitano Niguarda, USSD Cardiol Pediat, I-20126 Milan, Italy

[14] Fdn G Monasterio CNR Reg Toscana, Div Cardiovasc Med, I-56123 Pisa, Italy

[15] IRCCS Policlin San Donato, Dept Radiol, I-20097 San Donato Milanese, Milano, Italy

[16] ARNAS Civ, PO G Di Cristina, UOC Radiodiagnost, I-90123 Palermo, Italy

[17] Univ Verona, Dept Radiol, I-37100 Verona, Italy

[18] Univ Verona, Dept Med, Div Cardiol, I-37100 Verona, Italy

[19] Papa Giovanni XXIII Hosp, Dept Cardiol & Cardiovasc Surg, I-24100 Bergamo, Italy

[20] IRCCS Ist Giannina Gaslini, Radiol Unit, I-16147 Genoa, Italy

[21] IRCCS, Bambino Gesu Childrens Hosp, Dept Imaging, Adv Cardiothorac Imaging Unit, I-00100 Rome, Italy

[22] Gen & Univ Hosp, Pediat Cardiol Unit, I-43121 Parma, Italy

[23] Giannina Gaslini Res Inst & Children Hosp, Pediat Cardiol Dept, I-16100 Genoa, Italy

[24] Fdn G Monasterio CNR Reg Toscana, Inf Dept, I-541200 Massa, Italy

来源：

DIAGNOSTICS | 2023年 / 13卷 / 20期

关键词：

tetralogy of Fallot; cardiac magnetic resonance imaging; congenital heart disease; Italian registry; repaired tetralogy of Fallot; CONGENITAL HEART-DISEASE; MAGNETIC-RESONANCE; MARKERS;

D O I：

10.3390/diagnostics13203255

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Managing repaired tetralogy of Fallot (TOF) patients is still challenging despite the fact that published studies identified prognostic clinical or imaging data with rather good negative predictive accuracy but weak positive predictive accuracy. Heterogeneity of the initial anatomy, the surgical approach, and the complexity of the mechanism leading to dilation and ventricular dysfunction explain the challenge of predicting the adverse event in this population. Therefore, risk stratification and management of this population remain poorly standardized. Design: The CMR/CT WG of the Italian Pediatric Cardiology Society set up a multicenter observational clinical database of repaired TOF evaluations. This registry will enroll patients retrospectively and prospectively assessed by CMR for clinical indication in many congenital heart diseases (CHD) Italian centers. Data collection in a dedicated platform will include surgical history, clinical data, imaging data, and adverse cardiac events at 6 years of follow-up. Summary: The multicenter repaired TOF clinical database will collect data on patients evaluated by CMR in many CHD centers in Italy. The registry has been set up to allow future research studies in this population to improve clinical/surgical management and risk stratification of this population.

引用

页数：14

共 27 条

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