The relation between dietary phytochemical index and metabolic health status in overweight and obese adolescents

被引:1
作者
Tirani, Shahnaz Amani [1 ]
Lotfi, Keyhan [2 ,6 ]
Mirzaei, Saeideh [3 ]
Asadi, Ali [4 ]
Akhlaghi, Masoumeh [3 ]
Saneei, Parvane [5 ]
机构
[1] Isfahan Univ Med Sci, Sch Nutr & Food Sci, Dept Community Nutr, Nutr & Food Secur Res Ctr,Students Res Comm, POB 81745-151, Esfahan, Iran
[2] Univ Tehran Med Sci, Sch Nutr Sci & Dietet, Dept Community Nutr, Tehran, Iran
[3] Shiraz Univ Med Sci, Sch Nutr & Food Sci, Dept Community Nutr, Shiraz, Iran
[4] Univ Tehran, Sch Phys Educ & Sport Sci, Dept Exercise Physiol, Tehran, Iran
[5] Isfahan Univ Med Sci, Nutr & Food Secur Res Ctr, Sch Nutr & Food Sci, Dept Community Nutr, POB 81745-151, Esfahan, Iran
[6] Univ Tehran Med Sci, Students Sci Res Ctr, Tehran, Iran
关键词
OXIDATIVE STRESS; RISK-FACTORS; CHILDREN; ASSOCIATION; PREVALENCE; NUTRIENTS;
D O I
10.1038/s41598-023-39314-z
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Previous studies have rarely investigated dietary phytochemicals consumption in relation to metabolic health of adolescents. The current study was performed to investigate dietary phytochemical index (DPI) in relation to metabolic health status in overweight and obese adolescents. This cross-sectional study was conducted among 203 adolescents with overweight or obesity. Dietary intakes of participants were obtained through a validated 147-item food frequency questionnaire. DPI was calculated [(dietary energy derived from phytochemical-rich foods (kcal)/total daily energy intake (kcal)) ⨯100]. Glycemic and lipid profiles, blood pressure, and anthropometric indices were also measured. A metabolically unhealthy overweight/obesity (MUO) profile was determined based on the International Diabetes Federation (IDF) and IDF/Homeostasis Model Assessment Insulin Resistance (HOMA-IR) definitions. Study subjects had a mean age of 13.98 years and 50.2% of them were girls. According to IDF and IDF/HOMA-IR criteria, 38.9% (37 boys, and 42 girls) and 33% (35 boys, and 32 girls) of the study participants were respectively MUO. According to IDF and IDF/HOMA-IR definitions, adolescents in the third DPI tertile had respectively 61% (maximally-adjusted OR = 0.39, 95%CI 0.16-0.91) and 67% (maximally-adjusted OR = 0.33, 95%CI 0.13-0.83) lower odds of being MUO, compared to the first tertile. Stratified analysis by sex indicated that DPI was inversely related to MUO phenotype based on IDF criteria in girls (maximally-adjusted OR = 0.25, 95%CI 0.06-0.98), but not in boys. The current study found that adolescents with a higher dietary intake of phytochemicals have lower odds of being MUO, particularly among girls. However, further large-scale prospective cohort studies are required to confirm this finding.
引用
收藏
页数:10
相关论文
共 57 条
[11]  
Ezzati M, 2017, LANCET, V390, P2627, DOI [10.1016/S0140-6736(17)32129-3, 10.1016/s0140-6736(17)32129-3]
[12]  
Faghihimani Z., 2010, ARYA ATHEROSCLER J, V5
[13]   Childhood Obesity, Other Cardiovascular Risk Factors, and Premature Death [J].
Franks, Paul W. ;
Hanson, Robert L. ;
Knowler, William C. ;
Sievers, Maurice L. ;
Bennett, Peter H. ;
Looker, Helen C. .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (06) :485-493
[14]  
Fulgoni Victor L. III, 2020, Nutrition and Health (Bicester), V26, P243, DOI 10.1177/0260106020928664
[15]   Adolescent obesity and midlife cancer risk: a population-based cohort study of 2.3 million adolescents in Israel [J].
Furer, Ariel ;
Afek, Arnon ;
Sommer, Adir ;
Keinan-Boker, Lital ;
Derazne, Estela ;
Levi, Zohar ;
Tzur, Dorit ;
Tiosano, Shmuel ;
Shina, Avi ;
Glick, Yuval ;
Kark, Jeremy D. ;
Tirosh, Amir ;
Twig, Gilad .
LANCET DIABETES & ENDOCRINOLOGY, 2020, 8 (03) :216-225
[16]  
Garmaroudi GR., 2010, Payesh, V9, P137
[17]  
Ghaffarpour M., 1999, Tehran Nashre Olume Keshavarzy, V7, P42
[18]   Association between dietary phytochemical index and breast cancer: a case-control study [J].
Ghoreishy, Seyed Mojtaba ;
Aminianfar, Azadeh ;
Benisi-Kohansal, Sanaz ;
Azadbakht, Leila ;
Esmaillzadeh, Ahmad .
BREAST CANCER, 2021, 28 (06) :1283-1291
[19]   Self-esteem and quality of life in obese children and adolescents: A systematic review [J].
Griffiths, Lucy J. ;
Parsons, Tessa J. ;
Hill, Andrew J. .
INTERNATIONAL JOURNAL OF PEDIATRIC OBESITY, 2010, 5 (04) :282-304
[20]   Anti-inflammatory effects of flavonoids:: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-κB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-κB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages [J].
Hamalainen, Mari ;
Nieminen, Riina ;
Vuorela, Pia ;
Heinonen, Marina ;
Moilanen, Eeva .
MEDIATORS OF INFLAMMATION, 2007, 2007