Chemical Profiling and Antimicrobial Activity of Essential Oils from Hypericum adenotrichum Spach. An Endemic Species

被引:1
作者
Saltan, Nagehan [1 ]
Kose, Yavuz Bulent [1 ]
Kirci, Damla [2 ]
Goger, Fatih [3 ,4 ]
Demirci, Betul
机构
[1] Anadolu Univ, Fac Pharm, Dept Pharmaceut Bot, Eskisehir, Turkiye
[2] Selcuk Univ, Fac Pharm, Dept Pharmacognosy, Konya, Turkiye
[3] Afyonkarahisar Hlth Sci Univ, Fac Pharm, Dept Pharmaceut Bot, Afyonkarahisar, Turkiye
[4] Anadolu Univ, Fac Pharm, Dept Pharmacognosy, Eskisehir, Turkiye
来源
JOURNAL OF RESEARCH IN PHARMACY | 2023年 / 27卷 / 04期
关键词
Antimicrobial activity; GC; -MS; GC-FID; Hypericum adenotrichum; LC-MS; MS; PHYTOCHEMICAL ANALYSIS; VOLATILE CONSTITUENTS; PHENOLIC CONSTITUENTS; BIOACTIVE SUBSTANCES; VAR; CAPITATUM; ANTIOXIDANT; PLANT; PERFORATUM; CLUSIACEAE; TURKEY;
D O I
10.29228/jrp.449
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The purpose of this study was to determine the content of essential oils isolated from the herba and roots of Hypericum adenotrichum Spach., an endemic, wild-growing species of Turkish flora. Gas Chromatography-Mass Spectroscopy (GC-MS) and Gas Chromatography-Flame Ionization Detector (GC-FID) were used to examine the essential oils (EO). In the essential oils of the root of H. adenotrichum, the compounds were found, with undecane (64.4%), hexadecanoic acid (5.3%), and & alpha; -copaene (3.9%) as the primary components. Three significant herba compounds, germacrene D (13.3%), hexadecanoic acid (11.3%), and cadinene (6%) were found. Moreover, in this study antimicrobial effects of EO of endemic H. adenotrichum against Escherichia coli NRRL B-3008, Staphylococcus aureus ATCC 6538, Salmonella tymphirium ATCC 14028, Staphylococcus aureus ATCC 700699, Candida albicans ATCC 90028 and Candida krusei ATTC 6258. H. adenotrichum root and herba extracts were made, and LC-MS/MS analysis was used to determine the primary constituents of the extracts. The chemicals found in the herb and root, respectively, include 3-caffeoylquinic acid, 5-caffeoylquinic acid, quercetin hexoside, quinic acid, quercetin, and catechine.
引用
收藏
页码:1645 / 1657
页数:13
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