Microwave Sensor for the Determination of DMSO Concentration in Water-DMSO Binary Mixture

被引:2
作者
Harnsoongnoen, Supakorn [1 ]
Buranrat, Benjaporn [2 ]
机构
[1] Mahasarakham Univ, Fac Sci, Dept Phys, Biomimicry Sustainable Agr Hlth Environm & Energy, Kantarawichai Dist 44150, Maha Sarakham, Thailand
[2] Mahasarakham Univ, Fac Med, Muang Dist 44000, Maha Sarakham, Thailand
关键词
microwave sensor; hexagonal complementary ring resonator (HCRR); DMSO-water mixtures; interdigital capacitor; microstrip antenna; DIMETHYL-SULFOXIDE; MICROFLUIDIC SENSOR; NEUTRON-DIFFRACTION; SOLVENT MIXTURES; DIMETHYLSULFOXIDE; DYNAMICS; ASSOCIATION; RELAXATION; SYSTEM;
D O I
10.3390/mi14071378
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This research aims to develop a microwave sensor to accurately measure the concentration of dimethyl sulfoxide (DMSO) in water-DMSO binary mixtures. The proposed sensor will utilize microwave frequency measurements to determine the DMSO concentration, providing a non-invasive and efficient method for analyzing DMSO solutions. The research will involve the design, fabrication, and testing of the sensor, as well as the development of an appropriate calibration model. The outcomes of this study will contribute to improved monitoring and quality control in various fields, including pharmaceuticals, chemical synthesis, and biomedical research. The binary mixtures of dimethyl sulfoxide (DMSO) and water with varying concentrations were investigated in the frequency range of 1 GHz to 5 GHz at room temperature using a microwave sensor. The proposed microwave sensor design was based on an interdigital capacitor (IDC) microstrip antenna loaded with a hexagonal complementary ring resonator (HCRR). The performance of the sensor, fabricated using the print circuit board (PCB) technique, was validated through simulations and experiments. The reflection coefficient (S-11) and resonance frequency (F-r) of binary mixtures of DMSO and water solutions were recorded and analyzed for DMSO concentrations ranging from 0% v/v to 75% v/v. Mathematical models were developed to analyze the data, and laboratory tests showed that the sensor can detect levels of DMSO/water binary mixtures. The sensor is capable of detecting DMSO concentrations ranging from 0% v/v to 75% v/v, with a maximum sensitivity of 0.138 dB/% for S-11 and & UDelta;S-11 and 0.2 MHz/% for F-r and & UDelta;F-r at a concentration of 50% v/v. The developed microwave sensor can serve as an alternative for detecting DMSO concentrations in water using a simple and cost-effective technique. This method can effectively analyze a wide range of concentrations, including highly concentrated solutions, quickly and easily.
引用
收藏
页数:16
相关论文
共 60 条
[1]   Use of different DMSO concentrations for cryopreservation of autologous peripheral blood stem cell grafts does not have any major impact on levels of leukocyte- and platelet-derived soluble mediators [J].
Akkok, Cigdem Akalin ;
Liseth, Knut ;
Hervig, Tor ;
Ryningen, Anita ;
Bruserud, Oystein ;
Ersvaer, Elisabeth .
CYTOTHERAPY, 2009, 11 (06) :749-760
[2]   Measurement of DMS, DMSO, and DMSP in natural waters by automated sequential chemical analysis [J].
Asher, Elizabeth C. ;
Dacey, John W. H. ;
Jarnikova, Tereza ;
Tortell, Philippe D. .
LIMNOLOGY AND OCEANOGRAPHY-METHODS, 2015, 13 (09) :451-462
[3]   REAL-TIME MEASUREMENT OF DIMETHYL-SULFOXIDE IN AMBIENT AIR [J].
BERRESHEIM, H ;
TANNER, DJ ;
EISELE, FL .
ANALYTICAL CHEMISTRY, 1993, 65 (01) :84-86
[4]   Rydberg electron-transfer spectroscopy and ab initio studies of dimethylsulfoxide-water neutral and anion dimers [J].
Carles, S ;
Desfrançois, C ;
Schermann, JP ;
Bergès, J ;
Houée-Levin, C .
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2001, 205 (1-3) :227-232
[5]   Characterization of binary solvent mixtures of DMSO with water and other cosolvents [J].
Catalán, J ;
Díaz, C ;
García-Blanco, F .
JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (17) :5846-5852
[6]   High-pressure spectroscopic probe of hydrophobic hydration of the methyl groups in dimethyl sulfoxide [J].
Chang, HC ;
Jiang, JC ;
Feng, CM ;
Yang, YC ;
Su, CC ;
Chang, PJ ;
Lin, SH .
JOURNAL OF CHEMICAL PHYSICS, 2003, 118 (04) :1802-1807
[7]   Dielectric Permittivity Properties of Hydrated Polymers: Measurement and Connection to Ion Transport Properties [J].
Chang, Kevin ;
Geise, Geoffrey M. .
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 2020, 59 (12) :5205-5217
[8]   ASSOCIATION IN BINARY LIQUID SYSTEM DIMETHYL SULPHOXIDE-WATER [J].
COWIE, JM ;
TOPOROWSKI, PM .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1961, 39 (11) :2240-&
[9]   Differential microwave sensor for characterization of glycerol-water solutions [J].
Ebrahimi, Amir ;
Tovar-Lopez, Francisco J. ;
Scott, James ;
Ghorbani, Kamran .
SENSORS AND ACTUATORS B-CHEMICAL, 2020, 321 (321)
[10]   Microwave reflective biosensor for glucose level detection in aqueous solutions [J].
Ebrahimi, Amir ;
Scott, James ;
Ghorbani, Kamran .
SENSORS AND ACTUATORS A-PHYSICAL, 2020, 301