Therapeutic Efficacy of Benzimidazole and Its Analogs: An Update

被引：16

作者：

Basha, N. Jeelan ^{[1
]}

机构：

[1] Indian Acad Degree Coll Autonomous, Dept Chem, Bengaluru 560043, India

来源：

POLYCYCLIC AROMATIC COMPOUNDS | 2023年 / 43卷 / 07期

关键词：

Benzimidazole; medicinal drugs; antibacterial; antifungal; anticancer and antiviral activity; HIV-1; REVERSE-TRANSCRIPTASE; HUMAN CYTOMEGALOVIRUS; ANTIVIRAL ACTIVITY; NONNUCLEOSIDE INHIBITORS; BIOLOGICAL EVALUATION; DERIVATIVES; DESIGN; CANCER; ANTICANCER; FUNGICIDE;

D O I：

10.1080/10406638.2022.2118334

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Benzimidazoles, one of the nitrogen heterocycles, possess pharmaceutical and biological potential. This heterocycle has been known for pharmacological activities such as antifungal, antibacterial, and antiparasitic. The reports on the activities of the compounds containing this basic moiety are well-reported in the literature, specifically as anthelmintic and proton pump inhibitors. This review covers the synthesis of benzimidazole analogs by feasible methods from our laboratory. Also, the present review explores the recent reports on benzimidazole analogs designed as antibacterial, antifungal, anticancer, and antiviral agents.

引用

页码：6549 / 6569

页数：21

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