Visual search in Alzheimer's disease and amnesticmild cognitive impairment: An eye-tracking study

被引:0
作者
Boz, Hatice Eraslan [1 ,2 ]
Kocoglu, Koray [1 ]
Akkoyun, Muge [1 ]
Tufekci, Isil Yagmur [1 ]
Ekin, Merve [1 ]
Akdal, Gulden [1 ,3 ]
机构
[1] Dokuz Eylul Univ, Inst Hlth Sci, Dept Neurosci, Izmir, Turkiye
[2] Dokuz Eylul Univ, Dept Neurol, Unit Neuropsychol, Izmir, Turkiye
[3] Dokuz Eylul Univ, Dept Neurol, Izmir, Turkiye
关键词
Alzheimer's disease; amnestic mild cognitive impairment; finding objects; visual attention; visual; search; ASSOCIATION WORKGROUPS; DIAGNOSTIC GUIDELINES; NATIONAL INSTITUTE; ATTENTION IMPAIRMENTS; SCENE PERCEPTION; TIME-COURSE; RECOMMENDATIONS; DEMENTIA; DEFICITS; PERFORMANCE;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
INTRODUCTION: Visual search impairment is a potential cognitive marker for Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI). The aim of this study is to compare eyemovements during visual tracking inADand aMCI patients versus healthy controls (HCs). METHODS: A prospective cohort study included 32 AD and 37 aMCI patients, and 33 HCs. Each participant was asked to look at the target object in a visual stimulus containing one target and eight distractors, and eye movements were recorded with EyeLink 1000 Plus. RESULTS: AD patients had fewer fixations and shorter target fixation duration than aMCI patients and HCs. Fixation durations were also shorter in aMCI patients compared to HCs. Also, AD patients were more fixated on distractors than HCs. DISCUSSION: Our findings revealed that visual search is impaired in the early stages ofADand even aMCI, highlighting the importance of addressing visual processes in the Alzheimer's continuum.
引用
收藏
页码:759 / 768
页数:10
相关论文
共 69 条
[1]   Saccadic Eye Movements in Patients with Mild Cognitive Impairment: A Longitudinal Study [J].
Akkoyun, Muge ;
Kocoglu, Koray ;
Boz, Hatice Eraslan ;
Keskinoglu, Pembe ;
Akdal, Gulden .
JOURNAL OF MOTOR BEHAVIOR, 2023, 55 (04) :354-372
[2]  
Akkoyun Muge, 2023, ALZHEIMERS DEMENT, V19, pS4, DOI 10.1002/alz.065433
[3]   The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease [J].
Albert, Marilyn S. ;
DeKosky, Steven T. ;
Dickson, Dennis ;
Dubois, Bruno ;
Feldman, Howard H. ;
Fox, Nick C. ;
Gamst, Anthony ;
Holtzman, David M. ;
Jagust, William J. ;
Petersen, Ronald C. ;
Snyder, Peter J. ;
Carrillo, Maria C. ;
Thies, Bill ;
Phelps, Creighton H. .
ALZHEIMERS & DEMENTIA, 2011, 7 (03) :270-279
[4]   Visual and visuospatial short-term memory in mild cognitive impairment and Alzheimer disease: Role of attention [J].
Alescio-Lautier, B. ;
Michel, B. F. ;
Herrera, C. ;
Elahmadi, A. ;
Chambon, C. ;
Touzet, C. ;
Paban, V. .
NEUROPSYCHOLOGIA, 2007, 45 (08) :1948-1960
[5]  
[Anonymous], 1995, The visual brain in action
[6]   Determinants of Dwell Time in Visual Search: Similarity or Perceptual Difficulty? [J].
Becker, Stefanie I. .
PLOS ONE, 2011, 6 (03)
[7]  
Benton A., 1968, Cortex, V4, P344, DOI [10.1016/S0010-9452(68)80018-8, DOI 10.1016/S0010-9452(68)80018-8, 10.1016/S0010-9452, DOI 10.1016/S0010-9452]
[8]   VISUOSPATIAL JUDGMENT - CLINICAL TEST [J].
BENTON, AL ;
VARNEY, NR ;
HAMSHER, KD .
ARCHIVES OF NEUROLOGY, 1978, 35 (06) :364-367
[9]   A SIMPLE OBJECTIVE TECHNIQUE FOR MEASURING FLEXIBILITY IN THINKING [J].
Berg, Esta A. .
JOURNAL OF GENERAL PSYCHOLOGY, 1948, 39 (01) :15-22
[10]   Examination of eye movements during visual scanning of real-world images in Alzheimer's disease and amnestic mild cognitive impairment [J].
Boz, Hatice Eraslan ;
Kocoglu, Koray ;
Akkoyun, Muge ;
Tufekci, Isil Yagmur ;
Ekin, Merve ;
Ozcelik, Pinar ;
Akdal, Gulden .
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, 2023, 190 :84-93