Percutanous Electrochemotherapy (ECT) in Primary and Secondary Liver Malignancies: A Systematic Review

被引:12
作者
Granata, Vincenza [1 ]
Fusco, Roberta [2 ]
D'Alessio, Valeria [2 ]
Simonetti, Igino [1 ]
Grassi, Francesca [3 ]
Silvestro, Lucrezia [4 ]
Palaia, Raffaele [5 ]
Belli, Andrea [5 ]
Patrone, Renato [5 ]
Piccirillo, Mauro [5 ]
Izzo, Francesco [5 ]
机构
[1] IRCCS Napoli, Div Radiol, Ist Nazl Tumori IRCCS Fdn Pascale, I-80131 Naples, Italy
[2] Oncol Med & Res & Dev Div, I-80013 Naples, Italy
[3] Univ Campania Luigi Vanvitelli, Div Radiol, I-80127 Naples, Italy
[4] IRCCS Napoli, Div Clin Expt Oncol Abdomen, Ist Nazl Tumori IRCCS Fdn Pascale, I-80131 Naples, Italy
[5] IRCCS Napoli, Div Epatobiliary Surg Oncol, Ist Nazl Tumori IRCCS Fdn Pascale, I-80131 Naples, Italy
关键词
Electrochemotherapy; liver; percutaneous approach; HEPATOCELLULAR-CARCINOMA; RADIOFREQUENCY ABLATION; TRANSARTERIAL CHEMOEMBOLIZATION; IRREVERSIBLE ELECTROPORATION; PANCREATIC-CANCER; EUROPEAN RESEARCH; HEPATIC HILUM; METASTASES; METAANALYSIS; COMBINATION;
D O I
10.3390/diagnostics13020209
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The aim of the study was to analyse papers describing the use of Electrochemotherapy (ECT) in local treatment of primary and secondary liver tumours located at different sites and with different histologies. Other Local Ablative Therapies (LAT) are also discussed. Analyses of these papers demonstrate that ECT use is safe and effective in lesions of large size, independently of the histology of the treated lesions. ECT performed better than other thermal ablation techniques in lesions > 6 cm in size and can be safely used to treat lesions distant, close, or adjacent to vital structures. ECT spares vessel and bile ducts, is repeatable, and can be performed between chemotherapeutic cycles. ECT can fill the gap in local ablative therapies due to being lesions too large or localized in highly challenging anatomical sites.
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页数:14
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