Epidemiology of Inflammatory Bowel Diseases: A Population Study in a Healthcare District of North-West Italy

被引:31
作者
Caviglia, Gian Paolo [1 ]
Garrone, Angela [2 ]
Bertolino, Chiara [2 ]
Vanni, Riccardo [3 ]
Bretto, Elisabetta [1 ]
Poshnjari, Anxhela [1 ]
Tribocco, Elisa [1 ]
Frara, Simone [1 ]
Armandi, Angelo [1 ]
Astegiano, Marco [4 ]
Saracco, Giorgio Maria [1 ]
Bertolusso, Luciano [2 ]
Ribaldone, Davide Giuseppe [1 ]
机构
[1] Univ Turin, Dept Med Sci, I-10126 Turin, Italy
[2] ASL CN2 Alba Bra, I-12051 Alba, CN, Italy
[3] Michele & Pietro Ferrero Hosp, Unit Gastroenterol & Digest Endoscopy, I-12060 Verduno, Italy
[4] Molinette Mauriziano Hosp, AOU Citta Salute & Sci Torino, Unit Gastroenterol, I-10126 Turin, Italy
关键词
burden; incidence; Crohn's disease; prevalence; ulcerative colitis; PREVALENCE; IMPACT;
D O I
10.3390/jcm12020641
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The burden of inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is increasing worldwide. The aim of the present study was to investigate the clinical characteristics and the changing in epidemiology of IBD in the Healthcare District Bra, an area of North-West Italy accounting for 57,615 inhabitants as of 31 December 2021. Clinical and demographic data were retrieved from administrative databases and the medical records of general practitioners (n = 39) at Verduno Hospital. Prevalence and incidence rates were calculated for the time span 2016-2021 and compared to the 2001-2006 period. IBD prevalence was 321.2 per 100,000 population in 2021 and, compared with 2006 (200 per 100,000 population), the prevalence has increased at a rate of +46%. Similarly, the average incidence has increased from the period 2001-2006 (6.7 per 100,000 population/year) to the period 2016-2021 (18.0 per 100,000 population/year) at a rate of +169%; such an increase was greater for CD than UC. In the 2016-2021 period, the mean age at diagnosis was 42.0 +/- 17.4 years and 30.9% required at least one hospitalization, while 10.9% of patients underwent at least one surgery. In conclusion, the prevalence and incidence of IBD distinctly increased over a two decade period in the Healthcare District Bra paralleling the results of previous surveys from other Italian regions. These data warrant specific interventions to improve patients' management and resources' allocation.
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页数:8
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