Trends in smart drug delivery systems for targeting cancer cells

被引：22
作者：
Kandula, Sharanya [1 ,2 ]
Singh, Pravin Kumar [1 ,2 ]
Kaur, Gun Anit [1 ,2 ]
Tiwari, Ashutosh [1 ]
机构：
[1] IAAM, Inst Adv Mat, Gammalkilsvagen 18, S-59053 Ulrika, Sweden
[2] VBRI Innovat Ctr, 7-16 Kalkaji Extn, New Delhi 110019, India
来源：
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS | 2023年 / 297卷
关键词：
Targeted drug delivery systems; Conventional cancer therapy; Tumour microenvironment; Target ligands; Target anticancer therapy; IN-VITRO; ENHANCED PERMEABILITY; POLYMERIC MICELLES; AMINOPEPTIDASE N; NANOPARTICLES; DOXORUBICIN; FORMULATION; THERAPY; NANOMEDICINE; NANOCARRIERS;
D O I：
10.1016/j.mseb.2023.116816
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Cancer is a worldwide health issue, and there is still a considerable demand for innovative treatments. Smart drug delivery systems have gained popularity to improve the effectiveness and safety of cancer treatments. This article provides an update on the state of smart drug delivery systems for cancer. Beginning with a discussion of the limits of conventional therapy, this article introduces the topic of drug delivery's significance in cancer treatment. Next, it dive deep into the topic of targeted drug delivery and talk about passive targeting, active targeting, and physical targeting. Focusing on biocompatibility, toxicity, targeting efficiency, and cost, this article discusses current issues and future directions. Finally, a conclusion and future research directions section provides a brief overview of the study's key findings and suggests avenues for further investigation. Researchers and medical professionals interested in smart drug delivery systems for cancer cells may find this review paper to be an invaluable resource.
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页数：16
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