Magnitude of Low-density Lipoprotein Reduction and Impact on Major Cardiovascular Outcomes

被引：2

作者：

Giordano, Salvatore ^{[1
]}

Spadafora, Luigi ^{[2
]}

Biondi-Zoccai, Giuseppe ^{[3
,4
,5
]}

Bernardi, Marco ^{[2
]}

机构：

[1] Magna Graecia Univ Catanzaro, Dept Med & Surg Sci, Div Cardiol, Catanzaro, Italy

[2] Sapienza Univ Rome, Dept Clin Internal Med Anesthesiol & Cardiovasc Sc, Rome, Italy

[3] Sapienza Univ Rome, Dept Med Surg Sci & Biotechnol, Rome, Italy

[4] Mediterranea Cardioctr, Naples, Italy

[5] Sapienza Univ Rome, Dept Med Surg Sci & Biotechnol, Corso Repubbl 74, I-04100 Latina, Italy

来源：

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY | 2023年 / 81卷 / 01期

关键词：

SECONDARY PREVENTION; LDL-CHOLESTEROL; ASSOCIATION; MORTALITY; EFFICACY; SAFETY; RISK;

D O I：

10.1097/FJC.0000000000001376

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：15 / 17

页数：3

共 18 条

[1] Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials [J].

Baigent, C. ;

Blackwell, L. ;

Emberson, J. ;

Holland, L. E. ;

Reith, C. ;

Bhala, N. ;

Peto, R. ;

Barnes, E. H. ;

Keech, A. ;

Simes, J. ;

Collins, R. .

LANCET, 2010, 376 (9753) :1670-1681

[2] Canakinumab for secondary prevention of atherosclerotic disease [J].

Capodanno, Davide ;

Angiolillo, Dominick J. .

EXPERT OPINION ON BIOLOGICAL THERAPY, 2018, 18 (02) :215-220

[3] Reducing residual cardiovascular risk with novel therapies [J].

Davidson, Michael H. .

CURRENT OPINION IN LIPIDOLOGY, 2020, 31 (02) :108-110

[4]

Ennezat PV., 2022, J CARDIOVASC PHARM

[5] Clinical efficacy and safety of achieving very low LDL-cholesterol concentrations with the PCSK9 inhibitor evolocumab: a prespecified secondary analysis of the FOURIER trial [J].

Giugliano, Robert P. ;

Pedersen, Terje R. ;

Park, Jeong-Gun ;

De Ferrari, Gaetano M. ;

Gaciong, Zbigniew A. ;

Ceska, Richard ;

Toth, Kalman ;

Gouni-Berthold, Ioanna ;

Lopez-Miranda, Jose ;

Schiele, Francois ;

Mach, Francois ;

Ott, Brian R. ;

Kanevsky, Estelle ;

Pineda, Armando Lira ;

Somaratne, Ransi ;

Wasserman, Scott M. ;

Keech, Anthony C. ;

Sever, Peter S. ;

Sabatine, Marc S. .

LANCET, 2017, 390 (10106) :1962-1971

[6] 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines [J].

Grundy, Scott M. ;

Stone, Neil J. ;

Bailey, Alison L. ;

Beam, Craig ;

Birtcher, Kim K. ;

Blumenthal, Roger S. ;

Braun, Lynne T. ;

de Ferranti, Sarah ;

Faiella-Tommasino, Joseph ;

Forman, Daniel E. ;

Goldberg, Ronald ;

Heidenreich, Paul A. ;

Hlatky, Mark A. ;

Jones, Daniel W. ;

Lloyd-Jones, Donald ;

Lopez-Pajares, Nuria ;

Ndumele, Chiadi E. ;

Orringer, Carl E. ;

Peralta, Carmen A. ;

Saseen, Joseph J. ;

Smith, Sidney C., Jr. ;

Sperling, Laurence ;

Virani, Salim S. ;

Yeboah, Joseph .

CIRCULATION, 2019, 139 (25) :E1046-E1081

[7] 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) [J].

Mach, Francois ;

Baigent, Colin ;

Catapano, Alberico L. ;

Koskinas, Konstantinos C. ;

Casula, Manuela ;

Badimon, Lina ;

Chapman, M. John ;

De Backer, Guy G. ;

Delgado, Victoria ;

Ference, Brian A. ;

Graham, Ian M. ;

Halliday, Alison ;

Landmesser, Ulf ;

Mihaylova, Borislava ;

Pedersen, Terje R. ;

Riccardi, Gabriele ;

Richter, Dimitrios J. ;

Sabatine, Marc S. ;

Taskinen, Marja-Riitta ;

Tokgozoglu, Lale ;

Wiklund, Olov ;

Mueller, Christian ;

Drexel, Heinz ;

Aboyans, Victor ;

Corsini, Alberto ;

Doehner, Wolfram ;

Farnier, Michel ;

Gigante, Bruna ;

Kayikcioglu, Meral ;

Krstacic, Goran ;

Lambrinou, Ekaterini ;

Lewis, Basil S. ;

Masip, Josep ;

Moulin, Philippe ;

Petersen, Steffen ;

Petronio, Anna Sonia ;

Piepoli, Massimo Francesco ;

Pinto, Xavier ;

Raber, Lorenz ;

Ray, Kausik K. ;

Reiner, Zeljko ;

Riesen, Walter F. ;

Roffi, Marco ;

Schmid, Jean-Paul ;

Shlyakhto, Evgeny ;

Simpson, Iain A. ;

Stroes, Erik ;

Sudano, Isabella ;

Tselepis, Alexandros D. ;

Viigimaa, Margus .

EUROPEAN HEART JOURNAL, 2020, 41 (01) :111-188

[8] Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering A Systematic Review and Meta-analysis [J].

Navarese, Eliano P. ;

Robinson, Jennifer G. ;

Kowalewski, Mariusz ;

Kolodziejczak, Michalina ;

Andreotti, Felicita ;

Bliden, Kevin ;

Tantry, Udaya ;

Kubica, Jacek ;

Raggi, Paolo ;

Gurbel, Paul A. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2018, 319 (15) :1566-1579

[9] Effect of Evolocumab on Coronary Plaque Phenotype and Burden in Statin-Treated Patients Following Myocardial Infarction [J].

Nicholls, Stephen J. ;

Kataoka, Yu ;

Nissen, Steven E. ;

Prati, Francesco ;

Windecker, Stephan ;

Puri, Rishi ;

Hucko, Thomas ;

Aradi, Daniel ;

Herrman, Jean-Paul R. ;

Hermanides, Renicus S. ;

Wang, Bei ;

Wang, Huei ;

Butters, Julie ;

Di Giovanni, Giuseppe ;

Jones, Stephen ;

Pompili, Gianluca ;

Psaltis, Peter J. .

JACC-CARDIOVASCULAR IMAGING, 2022, 15 (07) :1308-1321

[10] Low-Dose Colchicine for Secondary Prevention of Cardiovascular Disease [J].

Nidorf, Stefan M. ;

Eikelboom, John W. ;

Budgeon, Charley A. ;

Thompson, Peter L. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 61 (04) :404-410

← 1 2 →