Synthesis of tetrahydroquinazolines from 2-aminobenzonitriles and alkylidene malonates via 1,4-conjugate addition and an unprecedented rearrangement reaction

被引：2

作者：

Porashar, Bikoshita ^{[1
]}

Behera, Bipin Kumar ^{[1
]}

Phukon, Hunmoina ^{[1
]}

Saikia, Anil K. ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Gauhati 781039, Assam, India

来源：

CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 32期

关键词：

QUINAZOLINONES; DERIVATIVES; AMINATION; EFFICIENT;

D O I：

10.1039/d4cc00240g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient methodology for the synthesis of highly diverse tetrahydroquinazoline scaffolds from 2-aminobenzonitriles and alkylidene malonates via 1,4-conjugate addition followed by an unprecedented rearrangement has been demonstrated. The methodology is further applicable for the synthesis of quinazolines and tetracyclic compounds. Some of the synthesized compounds exhibit photophysical properties.

引用

页码：4358 / 4361

页数：4

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