High prevalence of asymptomatic Anaplasma spp. infection in school-aged children in southeastern Gabon

被引：1

作者：

Ndjangangoye, Nal Kennedy ^{[1
]}

Nzassi, Patrice Makouloutou ^{[2
,3
]}

Bangueboussa, Felicien ^{[3
]}

Ntigui, Cherone Nancy Mbani Mpega ^{[1
,4
]}

Kouna, Lady Charlene ^{[1
]}

Moukodoum, Nancy Diamella ^{[1
]}

Atiga, Nick Chenis ^{[1
]}

Okouga, Alain Prince ^{[1
]}

Ontoua, Steede Seinnat ^{[1
,4
]}

Oyegue-Liabagui, Sandrine Lydie ^{[1
,6
]}

Lekana-Douki, Jean -Bernard ^{[1
,5
]}

机构：

[1] Unite Evolut Epidemiol & Resistances Parasitaires, CIRMF, Franceville, Gabon

[2] Inst Rech Ecol Tropicale IRET CENAREST, Dept Biol & Ecol Anim, Libreville, Gabon

[3] Unite Rech Ecol Sante, CIRMF, Franceville, Gabon

[4] Univ Sci & Tech Masuku USTM, Ecole Doctorale Regionale Afrique Infectiol Tropic, Franceville, Gabon

[5] Univ Sci Sante USS, Dept Parasitol Mycol, Libreville, Gabon

[6] Univ Sci & Tech Masuku USTM, Fac Sci, Dept Biol, Franceville, Gabon

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2024年 / 139卷

关键词：

Tick -borne diseases; Anaplasmataceae; Anaplasma; Ehrlichia; Diagnosis; Gabon; PLATYS;

D O I：

10.1016/j.ijid.2023.12.003

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Objectives: The objective of this study was to evaluate the detection rates of asymptomatic Anaplasma spp. and Ehrlichia spp. infections in children in southeastern Gabon. Methods: We conducted a cross-sectional study among school-aged children in southeastern Gabon between May and June 2021. Blood samples were collected. Anaplasmataceae, Anaplasma spp., and Ehrlichia spp. were detected by microscopy and polymerase chain reaction. Results: Of the 452 blood samples collected, 57.5% (n/N = 260/452) of the samples were positive for Anaplasma spp. and/or Ehrlichia spp. by microscopy, 86.9% (n/N = 393/452) of the samples were positive for both Anaplasmataceae and Anaplasma spp., and none of the samples were found positive for Ehrlichia spp. PCR was more sensitive and specific than microscopy for detection of Anaplasma spp.. Conclusions: In our study, a significant number of positive blood samples for Anaplasma spp. were found in school-aged children in southeastern Gabon. Further studies are needed to determine the prevalence of different species of Anaplasma, their pathogenicity, and their transmission patterns. (c) 2023 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )

引用

页码：192 / 194

页数：3

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