The effects of pomegranate consumption on lipid profile in adults: A systematic review and meta-analysis

被引:12
作者
Bahari, Hossein [1 ]
Rezaiian, Fatemeh [2 ]
Goudarzi, Kian [3 ]
Mirmohammadali, Seyedeh Nooshan [4 ]
Asbaghi, Omid [5 ,6 ]
Kolbadi, Kosar sadat Hosseini [7 ]
Naderian, Moslem [8 ,9 ]
Hosseini, Ali [8 ]
机构
[1] Mashhad Univ Med Sci, Fac Med, Dept Nutr, Mashhad, Iran
[2] Shahid Beheshti Univ Med Sci, Natl Nutr & Food Technol Res Inst, Fac Nutr Sci & Food Technol, Tehran, Iran
[3] Shahid Beheshti Univ Med Sci, Fac Med, Tehran, Iran
[4] Kansas State Univ, Dept Food Nutr Dietet & Hlth, Manhattan, KS USA
[5] Shahid Beheshti Univ Med Sci, Canc Res Ctr, Tehran, Iran
[6] Shahid Beheshti Univ Med Sci, Student Res Comm, Tehran, Iran
[7] Iran Univ Med Sci, Fac Med, Tehran, Iran
[8] Shiraz Univ Med Sci, Sch Pharm, Dept Pharmacognosy, Shiraz, Iran
[9] Yasuj Univ Med Sci, Med Plants Res Ctr, Yasuj, Iran
关键词
Pomegranate; Lipid profile; Hyperlipidemia; Systematic review; Meta; -analysis; CARDIOVASCULAR RISK-FACTORS; DOUBLE-BLIND; EXTRACT SUPPLEMENTATION; JUICE CONSUMPTION; OXIDATIVE STRESS; OBESE WOMEN; SEED OIL; DECREASES; INFLAMMATION; OVERWEIGHT;
D O I
10.1016/j.jff.2023.105727
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Background: Inconsistent evidence exists regarding the impact of pomegranate on lipid profile. Hence, this metaanalysis aimed to identify this effect.Methods: Database search was performed until June 2023 to identify eligible trials. Estimated 95 % confidence (CI) and the weighted mean difference (WMD) was used for triglycerides (TG), total cholesterol (TC), highdensity lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) through the randomeffects model.Results: Analyzing overall effect sizes for TG and TC demonstrated a significant reduction in TG levels (WMD12.65 mg/dL; 95%CI: -20.13 to -5.17; p = 0.001), whereas indicated no significant alteration in TC levels (WMD: -3.82 mg/dL; 95%CI: -7.66 to 0.02; p = 0.052). Pomegranate intake had a significant diminishing effect on LDL-C levels (WMD: -3.07 mg/dl; 95%CI: -5.70 to -0.44; p = 0.022), and a significant increasing influence on HDL-C levels (WMD: 2.53 mg/dl; 95%CI: 1.08 to 3.62; p < 0.001).Conclusion: Pomegranate consumption has a beneficial effect in improving TG, LDL-C, and HDL-C levels. Prospero registration code: CRD42023403365.
引用
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页数:13
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