A Review on Carbon Nanotubes Family of Nanomaterials and Their Health Field

被引:13
作者
Brito, Charles L. [1 ]
Silva, Joao V. [1 ]
Gonzaga, Rodrigo V. [1 ]
La-Scalea, Mauro A. [2 ]
Giarolla, Jeanine [1 ]
Ferreira, Elizabeth I. [1 ]
机构
[1] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Pharm, BR-05508000 Sao Paulo, Brazil
[2] Univ Fed Sao Paulo, Dept Chem, BR-09972270 Diadema, Brazil
来源
ACS OMEGA | 2024年 / 9卷 / 08期
关键词
DRUG-DELIVERY SYSTEM; LABEL-FREE DETECTION; PHOTOTHERMAL THERAPY; IN-VITRO; POLYELECTROLYTE COMPLEXES; PHOTODYNAMIC THERAPY; TARGETED DELIVERY; GENE-THERAPY; CANCER; SINGLE;
D O I
10.1021/acsomega.3c08824
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The use of carbon nanotubes (CNTs), which are nanometric materials, in pathogen detection, protection of environments, food safety, and in the diagnosis and treatment of diseases, as efficient drug delivery systems, is relevant for the improvement and advancement of pharmacological profiles of many molecules employed in therapeutics and in tissue bioengineering. It has contributed to the advancement of science due to the development of new tools and devices in the field of medicine. CNTs have versatile mechanical, physical, and chemical properties, in addition to their great potential for association with other materials to contribute to applications in different fields of medicine. As, for example, photothermal therapy, due to the ability to convert infrared light into heat, in tissue engineering, due to the mechanical resistance, flexibility, elasticity, and low density, in addition to many other possible applications, and as biomarkers, where the electronic and optics properties enable the transduction of their signals. This review aims to describe the state of the art and the perspectives and challenges of applying CNTs in the medical field. A systematic search was carried out in the indexes Medline, Lilacs, SciELO, and Web of Science using the descriptors "carbon nanotubes", "tissue regeneration", "electrical interface (biosensors and chemical sensors)", "photosensitizers", "photothermal", "drug delivery", "biocompatibility" and "nanotechnology", and "Prodrug design" and appropriately grouped. The literature reviewed showed great applicability, but more studies are needed regarding the biocompatibility of CNTs. The data obtained point to the need for standardized studies on the applications and interactions of these nanostructures with biological systems.
引用
收藏
页码:8687 / 8708
页数:22
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