A Review on Carbon Nanotubes Family of Nanomaterials and Their Health Field

被引:13
作者
Brito, Charles L. [1 ]
Silva, Joao V. [1 ]
Gonzaga, Rodrigo V. [1 ]
La-Scalea, Mauro A. [2 ]
Giarolla, Jeanine [1 ]
Ferreira, Elizabeth I. [1 ]
机构
[1] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Pharm, BR-05508000 Sao Paulo, Brazil
[2] Univ Fed Sao Paulo, Dept Chem, BR-09972270 Diadema, Brazil
来源
ACS OMEGA | 2024年 / 9卷 / 08期
关键词
DRUG-DELIVERY SYSTEM; LABEL-FREE DETECTION; PHOTOTHERMAL THERAPY; IN-VITRO; POLYELECTROLYTE COMPLEXES; PHOTODYNAMIC THERAPY; TARGETED DELIVERY; GENE-THERAPY; CANCER; SINGLE;
D O I
10.1021/acsomega.3c08824
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The use of carbon nanotubes (CNTs), which are nanometric materials, in pathogen detection, protection of environments, food safety, and in the diagnosis and treatment of diseases, as efficient drug delivery systems, is relevant for the improvement and advancement of pharmacological profiles of many molecules employed in therapeutics and in tissue bioengineering. It has contributed to the advancement of science due to the development of new tools and devices in the field of medicine. CNTs have versatile mechanical, physical, and chemical properties, in addition to their great potential for association with other materials to contribute to applications in different fields of medicine. As, for example, photothermal therapy, due to the ability to convert infrared light into heat, in tissue engineering, due to the mechanical resistance, flexibility, elasticity, and low density, in addition to many other possible applications, and as biomarkers, where the electronic and optics properties enable the transduction of their signals. This review aims to describe the state of the art and the perspectives and challenges of applying CNTs in the medical field. A systematic search was carried out in the indexes Medline, Lilacs, SciELO, and Web of Science using the descriptors "carbon nanotubes", "tissue regeneration", "electrical interface (biosensors and chemical sensors)", "photosensitizers", "photothermal", "drug delivery", "biocompatibility" and "nanotechnology", and "Prodrug design" and appropriately grouped. The literature reviewed showed great applicability, but more studies are needed regarding the biocompatibility of CNTs. The data obtained point to the need for standardized studies on the applications and interactions of these nanostructures with biological systems.
引用
收藏
页码:8687 / 8708
页数:22
相关论文
共 194 条
  • [1] Pt-, Rh-, Ru-, and Cu-Single-Wall Carbon Nanotubes Are Exceptional Candidates for Design of Anti-Viral Surfaces: A Theoretical Study
    Aasi, Aref
    Aghaei, Sadegh M.
    Moore, Matthew D.
    Panchapakesan, Balaji
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (15) : 1 - 23
  • [2] Carbon nanotubes in cancer therapy: a more precise look at the role of carbon nanotube-polymer interactions
    Adeli, Mohsen
    Soleyman, Rouhollah
    Beiranvand, Zahra
    Madani, Fahimeh
    [J]. CHEMICAL SOCIETY REVIEWS, 2013, 42 (12) : 5231 - 5256
  • [3] Application of carbon nanotubes in sensing/monitoring of pancreas and liver cancer
    Ahmadian, Elham
    Janas, Dawid
    Eftekhari, Aziz
    Zare, Najme
    [J]. CHEMOSPHERE, 2022, 302
  • [4] Synthesis, characterization and in vitro evaluation of methotrexate conjugated fluorescent carbon nanoparticles as drug delivery system for human lung cancer targeting
    Ajmal, Muhammad
    Yunus, Uzma
    Matin, Abdul
    Ul Haq, Noaman
    [J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2015, 153 : 111 - 120
  • [5] Adsorption analysis and mechanical characteristics of carbon nanotubes under physisorption of biological molecules in an aqueous environment using molecular dynamics simulations
    Ajori, S.
    Ameri, A.
    Ansari, R.
    [J]. MOLECULAR SIMULATION, 2020, 46 (05) : 388 - 397
  • [6] Potent in vitro antileishmanial activity of a nanoformulation of cisplatin with carbon nanotubes against Leishmania major
    Akhtari, Javad
    Faridnia, Roghiyeh
    Kalani, Hamed
    Bastani, Reza
    Fakhar, Mahdi
    Rezvan, Hossein
    Beydokhti, Amin Kazemi
    [J]. JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, 2019, 16 : 11 - 16
  • [7] Almeida Ricardo, 2020, Rev. katálysis, V23, P276, DOI 10.1590/1982-02592020v23n2p276
  • [8] Carbon nanotubes: potential medical applications and safety concerns
    Amenta, Valeria
    Aschberger, Karin
    [J]. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 2015, 7 (03) : 371 - 386
  • [9] Antimicrobial photodynamic activity of toluidine blue-carbon nanotube conjugate against Pseudomonas aeruginosa and Staphylococcus aureus - Understanding the mechanism of action
    Anju, V. T.
    Paramanantham, Parasuraman
    Lal, Sruthil S. B.
    Sharan, Alok
    Syed, Asad
    Bahkali, Needa A.
    Alsaedi, Marzouq H.
    Kaviyarasu, K.
    Busi, Siddhardha
    [J]. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2019, 27 : 305 - 316
  • [10] European Society of Cardiology and American College of Cardiology guidelines for redefinition of myocardial infarction: How to use existing assays clinically and for clinical trials
    Apple, FS
    Wu, AHB
    Jaffe, AS
    [J]. AMERICAN HEART JOURNAL, 2002, 144 (06) : 981 - 986