Severity of COVID-19 Pneumonia in Kidney Transplant Recipients According to SARS-CoV-2 Vaccination

被引：2
作者：
Choi, Seunghyeok [1 ]
Lee, Hanbi [1 ,2 ]
Eum, Sang Hun [2 ,3 ]
Min, Ji-Won [2 ,4 ]
Yoon, Hye Eun [2 ,3 ]
Yang, Chul Woo [1 ,2 ]
Chung, Byung Ha [1 ,2 ,5 ]
机构：
[1] Catholic Univ Korea, Coll Med, Seoul St Marys Hosp, Dept Internal Med,Div Nephrol, 222 Banpo Daero, Seoul 06591, South Korea
[2] Catholic Univ Korea, Coll Med, Transplantat Res Ctr, Seoul, South Korea
[3] Catholic Univ Korea, Incheon St Marys Hosp, Coll Med, Div Nephrol,Dept Internal Med, Seoul, South Korea
[4] Catholic Univ Korea, Bucheon St Marys Hosp, Coll Med, Div Nephrol,Dept Internal Med, Seoul, South Korea
[5] Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Transplantat Res Ctr, 222 Banpo Daero, Seoul 06591, South Korea
来源：
INFECTION AND CHEMOTHERAPY | 2023年 / 55卷 / 04期
关键词：
Kidney transplant recipient; COVID-19; pneumonia; SARS-CoV-2; vaccine; ANTIBODY;
D O I：
10.3947/ic.2023.0083
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We reviewed 24 kidney transplantat recipients (KTRs) who had radiologically confirmed coronavirus disease 2019 (COVID-19) pneumonia. Enrolled KTRs were divided into a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-vaccination (+) group (n = 18) and a vaccination (-) group (n = 6). Clinical outcomes of the two groups including death, pulmonary outcome, and renal outcome were compared. COVID-19 pneumonia was worse in vaccination (-) KTRs. Two out of six vaccination (-) KTRs needed continuous renal replacement therapy (CRRT) and mechanical ventilator (MV) and expired. In contrast, only one KTR expired and required CRRT and MV out of 18 vaccination (+) KTRs. Our results suggest that SARS-CoV-2 vaccination attenuates severity of COVID-19 pneumonia in KTRs.
引用
收藏
页码：505 / 509
页数：5
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