Elongational-flow elaboration of blend- and Janus-type polymeric nanoparticles

被引：1

作者：

Abdurahim, Javid ^{[1
]}

Serra, Christophe A. ^{[1
]}

Vauthier, Madeline ^{[1
]}

机构：

[1] Univ Strasbourg, CNRS, Inst Charles Sadron UPR 22, F-67000 Strasbourg, France

来源：

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS | 2023年 / 675卷

关键词：

Polymer; Janus; Nanoparticles; Elongational-flow; MICROFLUIDIC SYNTHESIS; PARTICLES; DRUG;

D O I：

10.1016/j.colsurfa.2023.132062

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Anisotropic particles, in shape or chemistry, have raised enthusiasm since they interact with their surrounding in unique ways, leading to complex assemblies that can be used in applications ranging from energy to health. In this study, two different types of polymeric nanoparticles, blend-type with two hydrophobic polymers and Janus type with hydrophobic and hydrophilic parts were produced thanks to an emulsification elongational-flow microprocess. Particles with controlled sizes and size distribution were successfully produced in one step and the effect of material (e.g. polymers' composition and concentration, solvent) and process (e.g. flow rates, emulsification time) parameters on nanoparticles' characteristics were thoroughly studied. Particles' diameter ranged from 90 to 200 nm, depending on the aforementioned parameters.

引用

页数：7

共 22 条

[1] Abdurahim J., 2022, J DRUG DELIV SCI TEC, P71, DOI DOI 10.1016/J.JDDST.2022.103358
[2] Review-Miniaturized and Microfluidic Devices for Automated Nanoparticle Synthesis
Amreen, Khairunnisa
Goel, Sanket
[J]. ECS JOURNAL OF SOLID STATE SCIENCE AND TECHNOLOGY, 2021, 10 (01)
[3] A new microfluidic setup for precise control of the polymer nanoprecipitation process and lipophilic drug encapsulation
Anton, Nicolas
Bally, Florence
Serra, Christophe A.
Ali, Ali
Arntz, Youri
Mely, Yves
Zhao, Minjie
Marchioni, Eric
Jakhmola, Anshuman
Vandamme, Thierry F.
[J]. SOFT MATTER, 2012, 8 (41) : 10628 - 10635
[4] Double emulsions prepared by two-step emulsification: History, state-of-the-art and perspective
Ding, Shukai
Serra, Christophe A.
Vandamme, Thierry F.
Yu, Wei
Anton, Nicolas
[J]. JOURNAL OF CONTROLLED RELEASE, 2019, 295 : 31 - 49
[5] Microfluidic-Assisted Production of Size-Controlled Superparamagnetic Iron Oxide Nanoparticles-Loaded Poly(methyl methacrylate) Nanohybrids
Ding, Shukai
Attia, Mohamed F.
Wallyn, Justine
Taddei, Chiara
Serra, Christophe A.
Anton, Nicolas
Kassem, Mohamad
Schmutz, Marc
Er-Rafik, Meriem
Messaddeq, Nadia
Collard, Alexandre
Yu, Wei
Giordano, Michele
Vandamme, Thierry F.
[J]. LANGMUIR, 2018, 34 (05) : 1981 - 1991
[6] Microfluidic nanoprecipitation systems for preparing pure drug or polymeric drug loaded nanoparticles: an overview
Ding, Shukai
Anton, Nicolas
Vandamme, Thierry F.
Serra, Christophe A.
[J]. EXPERT OPINION ON DRUG DELIVERY, 2016, 13 (10) : 1447 - 1460
[7] Ultrasonication-assisted preparation of water-in-oil emulsions and application to the removal of cationic dyes from water by emulsion liquid membrane - Part 1: Membrane stability
Djenouhat, Meriem
Hamdaoui, Oualid
Chiha, Mahdi
Samar, Mohamed H.
[J]. SEPARATION AND PURIFICATION TECHNOLOGY, 2008, 62 (03) : 636 - 641
[8] Predicting emulsion breakdown in the emulsion liquid membrane process: Optimization through response surface methodology and a particle swarm artificial neural network
Fetimi, Abdelhalim
Daas, Attef
Merouani, Slimane
Alswieleh, Abdullah M.
Hamachi, Mourad
Hamdaoui, Oualid
Kebiche-Senhadji, Ounissa
Yadav, Krishna Kumar
Jeon, Byong-Hun
Benguerba, Yacine
[J]. CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION, 2022, 176
[9] Parallel microfluidic synthesis of size-tunable polymeric nanoparticles using 3D flow focusing towards in vivo study
Lim, Jong-Min
Bertrand, Nicolas
Valencia, Pedro M.
Rhee, Minsoung
Langer, Robert
Jon, Sangyong
Farokhzad, Omid C.
Karnik, Rohit
[J]. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2014, 10 (02) : 401 - 409
[10] Mehlhorn H, 2016, PARASITOL RES MG, V8, P1, DOI 10.1007/978-3-319-25292-6_1

← 1 2 3 →