Measuring Absolute Coronary Flow and Microvascular Resistance by Thermodilution

被引:28
作者
Belmonte, Marta [1 ,2 ]
Gallinoro, Emanuele [1 ,3 ]
Pijls, Nico H. J. [4 ,19 ]
Bertolone, Dario Tino [1 ]
Keulards, Danielle C. J. [4 ,5 ]
Viscusi, Michele Mattia [1 ,2 ]
Storozhenko, Tatyana [1 ]
Mizukami, Takuya [1 ]
Mahendiran, Thabo [1 ,6 ]
Seki, Ruiko [1 ]
Fournier, Stephane [6 ]
de Vos, Annemiek [5 ]
Adjedj, Julien [7 ]
Barbato, Emanuele [8 ]
Sonck, Jeroen [1 ]
Damman, Peter [9 ]
Keeble, Thomas [10 ,11 ]
Fawaz, Samer [10 ,11 ]
Gutierrez-Barrios, Alejandro [12 ,13 ]
Paradies, Valeria [14 ]
Bouisset, Frederic [1 ]
Kern, Morton J. [15 ]
Fearon, William F. [16 ,17 ]
Collet, Carlos [1 ]
De Bruyne, Bernard [1 ,5 ,18 ]
机构
[1] Cardiovasc Ctr Aalst, OLV Clin, Aalst, Belgium
[2] Univ Federico II, Dept Adv Biomed Sci, Naples, Italy
[3] Galeazzi St Ambrogio Hosp, Cardiol Dept, Milan, Italy
[4] Catharina Hosp, Dept Cardiol, Eindhoven, Netherlands
[5] Eindhoven Univ Technol, Dept Biomed Engn, Eindhoven, Netherlands
[6] Lausanne Univ Hosp, Dept Cardiol, Lausanne, Switzerland
[7] Inst Arnault Tzanck, Dept Gastroenterol & Hepatol, St Laurent Du Var, France
[8] Sapienza Univ Rome, Dept Clin & Mol Med, Rome, Italy
[9] Radboud Univ Nijmegen, Med Ctr, Dept Cardiol, Nijmegen, Netherlands
[10] Mid South Essex NHS Fdn Trust, Essex Cardiothorac Ctr, Basildon, Essex, England
[11] Anglia Ruskin Sch Med, Med Technol Res Ctr, Chelmsford, Essex, England
[12] Hosp Puerta Mar, Cardiol Dept, Cadiz, Spain
[13] Inst Invest & Innovac Ciencias Biomed Cadiz, Cadiz, Spain
[14] Maasstad Hosp, Dept Cardiol, Rotterdam, Netherlands
[15] Vet Adm Long Beach Hlth Care Syst, Long Beach, CA USA
[16] Stanford Med Ctr Palo Alto, Dept Med, Div Cardiol, Palo Alto, CA USA
[17] VA Palo Alto Hlth Care Syst, Palo Alto, CA USA
[18] OLV Clin, Cardiovasc Ctr Aalst, Moorselbaan 164, B-9300 Aalst, Belgium
[19] Catharina Hosp, Cardiol, Michelangelo Ave 2, NL-5623 EJ Eindhoven, Netherlands
关键词
absolute coronary flow; ANOCA; continuous intracoronary thermodilution; coronary microcirculation; microvascular resistance reserve; BLOOD-FLOW; HYDROSTATIC-PRESSURE; CARDIAC-OUTPUT; RESERVE; DYSFUNCTION; VALIDATION; ALGORITHM; ISCHEMIA; ARTERIES;
D O I
10.1016/j.jacc.2023.12.014
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diagnosing coronary microvascular dysfunction remains challenging, primarily due to the lack of direct measurements of absolute coronary blood flow (Q) and microvascular resistance (R-mu). However, there has been recent progress with the development and validation of continuous intracoronary thermodilution, which offers a simplified and validated approach for clinical use. This technique enables direct quantification of Q and R-mu, leading to precise and accurate evaluation of the coronary microcirculation. To ensure consistent and reliable results, it is crucial to follow a standardized protocol when performing continuous intracoronary thermodilution measurements. This document aims to summarize the principles of thermodilution-derived absolute coronary flow measurements and propose a standardized method for conducting these assessments. The proposed standardization serves as a guide to ensure the best practice of the method, enhancing the clinical assessment of the coronary microcirculation.
引用
收藏
页码:699 / 709
页数:11
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