Diterpenoid alkaloids from Delphinium trichophorum

被引:2
|
作者
Pu, Yang-Li [1 ,2 ]
Tian, Ling-Feng [1 ]
Chen, Lin [1 ]
Deng, Meng-Yi [1 ,2 ]
Xie, Jiang [3 ]
Huang, Shuai [1 ,2 ,4 ]
Zhou, Xian-Li [1 ,2 ,4 ]
机构
[1] Southwest Jiaotong Univ, Sch Life Sci & Engn, Chengdu 610031, Peoples R China
[2] Southwest Jiaotong Univ, Yibin Inst, Yibin 644000, Peoples R China
[3] Southwest Jiaotong Univ, Affiliated Hosp, Peoples Hosp Chengdu 3, Chengdu 610031, Peoples R China
[4] Southwest Jiaotong Univ, Sch Life Sci & Engn, Chem & Biodivers Lab, Chengdu 610031, Peoples R China
关键词
Ranunculaceae; Delphinium; Delphinium trichophorum; diterpenoid alkaloids; anti-inflammatory; HETISINE; OXIDATION;
D O I
10.1080/10286020.2023.2209564
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Three new hetisine type C-20-diterpenoid alkaloids, named as trichophorines A-C (1-3), were isolated from Delphinium trichophorum, together with nine known alkaloids (4-12). Their structures were elucidated on the basis of spectroscopic data (1D, 2D NMR, single-crystal X-ray, and HR-ESI-MS). All compounds were evaluated for the inhibitory activities against LPS induced NO production in RAW 264.7 macrophage cells, and none of them showed considerable inhibitory activity.
引用
收藏
页码:1175 / 1183
页数:9
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