Diterpenoid alkaloids from Delphinium trichophorum

被引：2

作者：

Pu, Yang-Li ^{[1
,2
]}

Tian, Ling-Feng ^{[1
]}

Chen, Lin ^{[1
]}

Deng, Meng-Yi ^{[1
,2
]}

Xie, Jiang ^{[3
]}

Huang, Shuai ^{[1
,2
,4
]}

Zhou, Xian-Li ^{[1
,2
,4
]}

机构：

[1] Southwest Jiaotong Univ, Sch Life Sci & Engn, Chengdu 610031, Peoples R China

[2] Southwest Jiaotong Univ, Yibin Inst, Yibin 644000, Peoples R China

[3] Southwest Jiaotong Univ, Affiliated Hosp, Peoples Hosp Chengdu 3, Chengdu 610031, Peoples R China

[4] Southwest Jiaotong Univ, Sch Life Sci & Engn, Chem & Biodivers Lab, Chengdu 610031, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2023年 / 25卷 / 12期

关键词：

Ranunculaceae; Delphinium; Delphinium trichophorum; diterpenoid alkaloids; anti-inflammatory; HETISINE; OXIDATION;

D O I：

10.1080/10286020.2023.2209564

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new hetisine type C-20-diterpenoid alkaloids, named as trichophorines A-C (1-3), were isolated from Delphinium trichophorum, together with nine known alkaloids (4-12). Their structures were elucidated on the basis of spectroscopic data (1D, 2D NMR, single-crystal X-ray, and HR-ESI-MS). All compounds were evaluated for the inhibitory activities against LPS induced NO production in RAW 264.7 macrophage cells, and none of them showed considerable inhibitory activity.

引用

页码：1175 / 1183

页数：9

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