The incremental value of myocardial viability, evaluated by 18F-fluorodeoxyglucose positron emission tomography, and cardiovascular magnetic resonance for mortality prediction in patients with previous myocardial infarction and symptomatic heart failure

被引：2

作者：

Kazakauskaite, Egle ^{[1
,2
]}

Vajauskas, Donatas ^{[1
,2
]}

Bardauskiene, Lina ^{[1
,2
]}

Ordiene, Rasa ^{[1
,2
]}

Zabiela, Vytautas ^{[1
,2
]}

Zaliaduonyte, Diana ^{[1
,2
]}

Gustiene, Olivija ^{[1
,2
]}

Lapinskas, Tomas ^{[1
,2
]}

Jurkevicius, Renaldas ^{[1
,2
]}

机构：

[1] Lithuanian Univ Hlth Sci, Dept Cardiol, Hosp Kauno Klin, Kaunas, Lithuania

[2] Lithuanian Univ Hlth Sci, Kaunas, Lithuania

来源：

PERFUSION-UK | 2023年 / 38卷 / 06期

关键词：

myocardial viability; strain-encoded imaging; 18F-fluorodeoxyglucose positron emission tomography; myocardial perfusion imaging; late gadolinium enhancement; LEFT-VENTRICULAR DYSFUNCTION; LATE GADOLINIUM ENHANCEMENT; CORONARY-ARTERY-DISEASE; STRAIN-ENCODED MRI; REVASCULARIZATION; QUANTIFICATION; TRANSMURALITY; SOCIETY;

D O I：

10.1177/02676591221100739

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objectives To find the imaging mortality predictors in patients with previous myocardial infarction (MI), symptomatic heart failure (HF), and reduced left ventricle (LV) ejection fraction (EF). Methods for the study 39 patients were selected prospectively with prior MI, symptomatic HF, and LVEF <= 40%. All patients underwent transthoracic echocardiography (TTE), single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI), 18F-FDG positron emission tomography (FDG PET). 31 patients underwent cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE). Patients were divided into two groups: 1 group - cardiac death; 2 group - no cardiac death. Myocardial scars were assessed on a 5-point-scale. Follow-up data was obtained. Results Imaging features disclosed significant difference (p < 0.05) of defect score (CMR and SPECT-PET), LV end-diastolic diameter (EDD) (TTE), LVEDD index (CMR), LV global longitudinal strain (CMR) and LV global circumferential strain (CMR) between the groups. Predictors of cardiac death were: LVEDD index (TTE) and LV global longitudinal strain. The cut-off values to predict cardiac death were: defect score (CMR) 25 (AUC, 79.5%; OR 1.8, 95% CI 1.2-2.7), SPECT-PET defect score 22 (AUC, 73.9%; OR 0.5, 95% CI 0.3-0.7), LVEDD (TTE) 58 mm (AUC, 88.4%; OR 23.6, 95% CI 2.6-217.7), LVEDDi 30 mm/m(2) (TTE) (AUC, 73.6%; OR 22.0, 95% CI 1.9-251.5), LVEDDi 33.6 mm/m(2) (CMR) (AUC, 73.6%; OR 22.0, 95% CI 1.9-251.5), LV global longitudinal strain -13.4 (AUC, 87.8%; OR 2.1, 95% CI 1.2-3.7) and LV global circumferential strain -16.3 (AUC, 76.1%; OR 1.9, 95% CI 1.2-3.0). Conclusions Imaging features, such as defect score (CMR) >25, SPECT-PET defect score >22, LVEDD (TTE) >58 mm, LVEDDi (TTE) >30 mm/m(2), LVEDDi (CMR) >33.6 mm/m(2), LV global longitudinal strain -13.4 and LV global circumferential strain -16.3, may increase sensitivity and specificity of FDG PET and LGE CMR predicting of late mortality.

引用

页码：1288 / 1297

页数：10

共 27 条

[1] Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: A meta-analysis [J].