The Phase 2 CARTITUDE-2 Trial: Updated Efficacy and Safety of Ciltacabtagene Autoleucel in Patients with Multiple Myeloma and 1-3 Prior Lines of Therapy (Cohort A) and with Early Relapse after First Line Treatment (Cohort B)

被引：15

作者：

Hillengass, Jens ^{[1
]}

Cohen, Adam D. ^{[2
]}

Agha, Mounzer E. ^{[3
]}

Delforge, Michel ^{[4
]}

Kerre, Tessa ^{[5
]}

Roeloffzen, Wilfried ^{[6
]}

Einsele, Hermann ^{[7
]}

Goldschmidt, Hartmut ^{[8
]}

Weisel, Katja ^{[9
]}

Raab, Marc S. ^{[10
,11
]}

Scheid, Christof ^{[12
]}

Anguille, Sebastien ^{[13
]}

Sonneveld, Pieter ^{[14
]}

Zweegman, Sonja ^{[15
]}

Schecter, Jordan M. ^{[16
]}

de Braganca, Kevin C. ^{[16
]}

Jackson, Carolyn Chang ^{[16
]}

Vlummens, Philip ^{[17
]}

Varsos, Helen ^{[16
]}

Corsale, Christina ^{[16
]}

Madduri, Deepu ^{[16
]}

Yeh, Tzu-Min ^{[16
]}

Mistry, Pankaj ^{[18
]}

Roccia, Tito ^{[19
]}

Song, Qingxuan ^{[16
]}

Akram, Muhammad ^{[20
]}

Costa Filho, Octavio ^{[20
]}

Geng, Dong ^{[20
]}

Cohen, Yael C. ^{[21
,22
]}

van de Donk, Niels W. C. J. ^{[15
]}

机构：

[1] Roswell Pk, Buffalo, NY USA

[2] Univ Penn, Perelman Sch Med, Abramson Canc Ctr, Philadelphia, PA USA

[3] UPMC Hillman Canc Ctr, Pittsburgh, PA USA

[4] Univ Leuven, Leuven, Belgium

[5] Ghent Univ Hosp, Ghent, Belgium

[6] Univ Med Ctr Groningen, Dept Hematol, Groningen, Netherlands

[7] Univ Klinikum Wurzburg, Med Klin & Poliklin 2, Wurzburg, Germany

[8] Univ Hosp Heidelberg, GMMG Study Grp, Internal Med 5, Heidelberg, Germany

[9] Univ Med Ctr Hamburg Eppendorf, Hamburg, Germany

[10] Univ Hosp Heidelberg, Heidelberg, Germany

[11] German Canc Res Ctr, Clin Cooperat Unit Mol Hematol Oncol, Heidelberg, Germany

[12] Univ Cologne, Cologne, Germany

[13] Univ Antwerp, Antwerp Univ Hosp, Vaccine & Infect Dis Inst, Ctr Cell Therapy & Regenerat Med, Edegem, Belgium

[14] Univ Med Ctr Rotterdam, Dept Hematol, Erasmus MC, Rotterdam, Netherlands

[15] Vrije Univ Amsterdam, Amsterdam Univ Med Ctr, Amsterdam, Netherlands

[16] Janssen Res & Dev, Raritan, NJ USA

[17] Janssen Res & Dev, Beerse, Belgium

[18] Janssen Res & Dev, High Wycombe, Bucks, England

[19] Janssen Global Serv, Raritan, NJ USA

[20] Legend Biotech USA Inc, Somerset, NJ USA

[21] Tel Aviv Univ, Tel Aviv Sourasky Ichilov Med Ctr, Tel Aviv, Israel

[22] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel

来源：

BLOOD | 2023年 / 142卷

关键词：

D O I：

10.1182/blood-2023-178882

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页数：6