Imaging DNA origami by fluorescence in situ hybridization

被引：3
作者：
Patino, Tania [1 ]
机构：
[1] Eindhoven Univ Technol, Inst Complex Mol Syst, Biomed Engn Dept, Eindhoven, Netherlands
来源：
NATURE NANOTECHNOLOGY | 2024年 / 19卷 / 01期
关键词：
D O I：
10.1038/s41565-023-01556-3
中图分类号：
TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Conserved regions of the circular DNA sequence of the M13mp18 bacteriophage, which is used as a scaffold for DNA origami construction, are targeted with specific hybridization-chain-reaction probes. The probes enable sensitive detection of DNA origami nanostructures in cells, organoids and tissues to assess their biodistribution and stability.
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页码：1 / 2
页数：2
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