Pyruvate kinase deficiency mutant gene carriage in stray cats and rescued cats from animal hoarding in Hokkaido, Japan

被引：0

作者：

Ueno, Hiroshi ^{[1
,2
,9
]}

Itoh, Tomohito ^{[3
]}

Nasuno, Toyohiko ^{[4
]}

Konno, Wataru ^{[1
]}

Kondo, Atsushi ^{[5
]}

Konishi, Ikuo ^{[6
]}

Inukai, Hisao ^{[7
]}

Kokubo, Daiki ^{[1
]}

Isaka, Mitsuhiro ^{[1
]}

Islam, Md Shafiqul ^{[8
]}

Yamato, Osamu ^{[8
]}

机构：

[1] Rakuno Gakuen Univ, Sch Vet Med, Dept Compan Anim Clin Sci, Ebetsu, Hokkaido, Japan

[2] Kyoto Univ, Ctr Evolutionary Origins Human Behav, Natl BioResource Project Japanese Macaques, Inuyama, Aichi, Japan

[3] Livestock Improvement Assoc Japan Inc, Maebashi Inst Anim Sci, Gunma, Japan

[4] Nekoiro Clin, Kutchan, Hokkaido, Japan

[5] Takahashi Anim Hosp, Assabu, Hokkaido, Japan

[6] Palk Anim Hosp, Sapporo, Hokkaido, Japan

[7] Neko No byoin, Kitami, Hokkaido, Japan

[8] Kagoshima Univ, Joint Fac Vet Med, Lab Clin Pathol, Kagoshima, Japan

[9] Kyoto Univ, Ctr Evolutionary Origins Human Behav, Natl BioResource Project Japanese Macaques, Kanrin 41-2, Inuyama, Aichi 4848506, Japan

来源：

JOURNAL OF VETERINARY MEDICAL SCIENCE | 2023年 / 85卷 / 09期

关键词：

animal hoarding cat; microsatellite marker; mutant allele frequency; pyruvate kinase deficiency; stray cat; DOMESTIC CAT; LINKAGE MAP;

D O I：

10.1292/jvms.23-0091

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The mutant allele frequency of the Pyruvate kinase (PK) gene has been investigated mostly in pure breed cats. We investigated the PK mutant gene in stray and animal hoarding mongrel cats in Hokkaido, Japan. We also investigated the kinship of individuals carrying the mutant gene. Genotyping was conducted using the previously reported real-time PCR method. Fourteen microsatellite markers were used to identify the parents and offspring of cats carrying the PK mutant gene, and some kinship such as parent-offspring and siblings was observed. Some stray and animal hoarding cats carried the PK mutation gene and that consanguinity was confirmed among these cats indicated that the PK mutation gene was spread by unregulated interbreeding.

引用

页码：972 / 976

页数：5

共 1 条

[1] Real-time PCR genotyping assay for feline erythrocyte pyruvate kinase deficiency and mutant allele frequency in purebred cats in Japan
Kushida, Kazuya
Giger, Urs
Tsutsui, Toshihiko
Inaba, Megumi
Konno, Yoshio
Hayashi, Kureha
Noguchi, Kana
Yabuki, Akira
Mizukami, Keijiro
Kohyama, Moeko
Endo, Yasuyuki
Yamato, Osamu
JOURNAL OF VETERINARY MEDICAL SCIENCE, 2015, 77 (06) : 743 - 746

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