Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies

被引：4

作者：

Furie, Nadav ^{[1
,2
]}

Mandelboim, Michal ^{[2
,3
,4
]}

Zuckerman, Neta ^{[2
,3
,4
]}

Belkin, Ana ^{[5
,6
]}

Seluk, Lior ^{[1
,2
]}

Shafran, Inbal ^{[1
,2
]}

Mass, Ronen ^{[1
]}

Levy, Liran ^{[1
,2
]}

Chatterji, Sumit ^{[1
]}

Baltaxe, Erik ^{[1
,2
]}

Peled, Michael ^{[1
,2
]}

Shulimzon, Tiberiu ^{[1
]}

Avigdor, Abraham ^{[2
,7
]}

Amit, Sharon ^{[8
]}

Onn, Amir ^{[1
,2
]}

Marom, Edith M. ^{[2
,9
]}

Rahav, Galia ^{[2
,10
]}

Segel, Michael J. ^{[1
,2
,11
]}

机构：

[1] Sheba Med Ctr, Inst Pulmonol, Tel Hashomer, Israel

[2] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel

[3] Minist Hlth, Publ Hlth Serv, Cent Virol Lab, Tel Hashomer, Israel

[4] Sheba Med Ctr, Tel Hashomer, Israel

[5] Sheba Med Ctr, Internal Med D, Tel Hashomer, Israel

[6] Sheba Med Ctr, Infect Dis Unit, Tel Hashomer, Israel

[7] Sheba Med Ctr, Div Hematol & Bone Marrow Transplantat, Ramat Gan, Israel

[8] Sheba Med Ctr, Microbiol Lab, Tel Hashomer, Israel

[9] Sheba Med Ctr, Dept Diagnost Radiol, Tel Hashomer, Israel

[10] Sheba Med Ctr, 2 Derech Sheba, IL-52621 Ramat Gan, Israel

[11] Sheba Med Ctr, Inst Pulmonol, 2 Derech Sheba, IL-52621 Ramat Gan, Israel

来源：

OPEN FORUM INFECTIOUS DISEASES | 2023年 / 10卷 / 10期

关键词：

antibody therapy; COVID19; immune globulins; monoclonal antibody; SARS-CoV-2; SARS-COV-2; THERAPY;

D O I：

10.1093/ofid/ofad464

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report 8 cases of persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in patients previously treated with anti-CD20 monoclonal antibodies. Polymerase chain reaction of nasopharyngeal swabs for SARS-CoV-2 was negative in most cases; viral cell cultures confirmed that viable SARS-Co-2 virus was present. Four patients were treated with anti-SARS-CoV-2 hyperimmune globulins with rapid resolution of disease.

引用

页数：4

共 11 条

[11] Persistent COVID-19 Pneumonia and Failure to Develop Anti-SARS-CoV-2 Antibodies During Rituximab Maintenance Therapy for Follicular Lymphoma
Yasuda, Hajime
Tsukune, Yutaka
Watanabe, Naoki
Sugimoto, Kazuya
Uchimura, Ayana
Tateyama, Misa
Miyashita, Yosuke
Ochi, Yusuke
Komatsu, Norio
[J]. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2020, 20 (11) : 774 - 776

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