Effect of moderate exercise on osteoarthritis

被引:11
作者
Deng, Xiaofeng [1 ]
Xu, Haoran [2 ]
Hao, Xiaoxia [1 ]
Liu, Jiawei [1 ]
Shang, Xingru [1 ]
Xu, Tao [1 ]
机构
[1] Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Rehabil, Wuhan, Peoples R China
[2] Huazhong Univ Sci & Technol, Tongji Med Coll, Tongji Hosp, Dept Orthoped, Wuhan, Peoples R China
基金
中国国家自然科学基金;
关键词
moderate exercise; osteoarthritis; cartilage; exercise intensity; SYMPTOMATIC KNEE OSTEOARTHRITIS; BONE MORPHOGENETIC PROTEINS; SUBCHONDRAL BONE; RAT MODEL; ARTICULAR-CARTILAGE; AQUATIC EXERCISE; MUSCLE STRENGTH; OLDER-PEOPLE; PAIN; PROGRAM;
D O I
10.1530/EOR-22-0119
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
. Osteoarthritis (OA) is a chronic degenerative disease, which can cause a series of symptoms including pain and functional limitation, thus severely decreasing quality of life. . OA pathogenesis can be categorized into four levels, including risk factors, potential mechanisms, intraarticular degeneration phenotype, and substantive histological changes. . Moderate exercise can alleviate OA at all levels of pathogenesis, while excessive exercise may have adverse effects. . Based on rat-related original research, the parameters of moderate exercise and the effect of improving osteoarthritis have been comprehensively summarized. . Based on the extensive randomized controlled trial studies, results show various moderate exercises can improve the symptom and prognosis of OA in clinical settings. . This review gives an overview of the pathogenesis of OA and the mechanisms as well as clinical examples of moderate exercise treatment, aimed at providing rationale and evidence for moderate exercise in the treatment of OA to facilitate the provision of appropriate exercise therapy for OA patients.
引用
收藏
页码:148 / 161
页数:14
相关论文
共 117 条
[1]   Deleterious effects of osteoarthritis on the structure and function of the meniscal enthesis [J].
Abraham, A. C. ;
Pauly, H. M. ;
Donahue, T. L. Haut .
OSTEOARTHRITIS AND CARTILAGE, 2014, 22 (02) :275-283
[2]   Osteoarthritis Pathology, Diagnosis, and Treatment Options [J].
Abramoff, Benjamin ;
Caldera, Franklin E. .
MEDICAL CLINICS OF NORTH AMERICA, 2020, 104 (02) :293-+
[3]   Effects of neuromuscular training (NEMEX-TJR) on patient-reported outcomes and physical function in severe primary hip or knee osteoarthritis: a controlled before-and-after study [J].
Ageberg, Eva ;
Nilsdotter, Anna ;
Kosek, Eva ;
Roos, Ewa M. .
BMC MUSCULOSKELETAL DISORDERS, 2013, 14
[4]   Effect of 6-week retro or forward walking program on pain, functional disability, quadriceps muscle strength, and performance in individuals with knee osteoarthritis: a randomized controlled trial (retro-walking trial) [J].
Alghadir, Ahmad H. ;
Anwer, Shahnawaz ;
Sarkar, Bibhuti ;
Paul, Ashis K. ;
Anwar, Dilshad .
BMC MUSCULOSKELETAL DISORDERS, 2019, 20 (1)
[5]   Effect of physical activity and dietary restriction interventions on weight loss and the musculoskeletal function of overweight and obese older adults with knee osteoarthritis: a systematic review and mixed method data synthesis [J].
Alrushud, Asma S. ;
Rushton, Alison B. ;
Kanavaki, Archontissa M. ;
Greig, Carolyn A. .
BMJ OPEN, 2017, 7 (06)
[6]   Pyroptosis Plays a Role in Osteoarthritis [J].
An, Senbo ;
Hu, Huiyu ;
Li, Yusheng ;
Hu, Yihe .
AGING AND DISEASE, 2020, 11 (05) :1146-1156
[7]   Fall Risk and Utilization of Balance Training for Adults With Symptomatic Knee Osteoarthritis: Secondary Analysis From a Randomized Clinical Trial [J].
Anderson, Monica L. ;
Allen, Kelli D. ;
Golightly, Yvonne M. ;
Arbeeva, Liubov S. ;
Goode, Adam ;
Huffman, Kim M. ;
Schwartz, Todd A. ;
Hill, Carla H. .
JOURNAL OF GERIATRIC PHYSICAL THERAPY, 2019, 42 (02) :E39-E44
[8]   Interleukin-10 and collagen type II immunoexpression are modulated by photobiomodulation associated to aerobic and aquatic exercises in an experimental model of osteoarthritis [J].
Assis, Livia ;
Tim, Carla ;
Magri, Angela ;
Fernandes, Kelly Rossetti ;
Vassao, Patricia Gabrielli ;
Muniz Renno, Ana Claudia .
LASERS IN MEDICAL SCIENCE, 2018, 33 (09) :1875-1882
[9]   Musculoskeletal Atrophy in an Experimental Model of Knee Osteoarthritis The Effects of Exercise Training and Low-Level Laser Therapy [J].
Assis, Livia ;
Almeida, Thais ;
Milares, Luiz Paulo ;
dos Passos, Nayara ;
Araujo, Bruna ;
Bublitz, Caroline ;
Veronez, Suellen ;
Muniz Renno, Ana Claudia .
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, 2015, 94 (08) :609-616
[10]   Therapeutic Exercise [J].
Barker, Kim ;
Eickmeyer, Sarah .
MEDICAL CLINICS OF NORTH AMERICA, 2020, 104 (02) :189-+