Case-crossover study for the association between increased hospital admissions for respiratory diseases and the increase in atmospheric PM2.5 and PM2.5-bound trace elements in Pretoria, South Africa

被引：1
|
作者：
Howlett-Downing, Chantelle [1 ]
Boman, Johan [2 ]
Molnar, Peter [3 ]
Shirinde, Joyce [1 ]
Wichmann, Janine [1 ]
机构：
[1] Univ Pretoria, Fac Hlth Sci, Sch Hlth Syst & Publ Hlth, Gezina, South Africa
[2] Univ Gothenburg, Dept Chem & Mol Biol, Atmospher Sci Div, Gothenburg, Sweden
[3] Univ Gothenburg, Sahlgrenska Acad, Inst Med, Dept Occupational & Environm Med, Gothenburg, Sweden
来源：
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH | 2024年 / 34卷 / 03期
基金：
新加坡国家研究基金会;
关键词：
Respiratory disorders; < PM2 5; case-crossover; Pretoria; Tapp; AMBIENT AIR-POLLUTION; DAILY MORTALITY; HEALTH; CONSTITUENTS; COMPONENTS; EXPOSURE;
D O I：
10.1080/09603123.2023.2229256
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Outdoor PM2.5 was sampled in Pretoria, 18 April 2017 to 28 February 2020. A case-crossover epidemiology study was associated for increased PM2.5 and trace elements with increased hospital admissions for respiratory disorders (J00-J99). The results included a significant increase in hospital admissions, with total PM2.5 of 2.7% (95% CI: 0.6, 4.9) per 10 & mu;g & BULL;m(-3) increase. For the trace elements, Ca of 4.0% (95% CI: 1.4%-6.8%), Cl of 0.7% (95% CI: 0.0%-1.4%), Fe of 3.3% (95% CI: 0.5%-6.1%), K of 1.8% (95% CI: 0.2-3.5) and Si of 1.3% (95% CI: 0.1%-2.5%). When controlling for PM2.5, only Ca of 3.2% (95% CI: 0.3, 6.1) and within the 0-14 age group by 5.2% (95% CI: 1.5, 9.1). Controlling for a co-pollutant that is highly correlated with PM2.5 does reduce overestimation, but further studies should include deposition rates and parallel sampling analysis.
引用
收藏
页码：1551 / 1565
页数：15
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