Alzheimer's Disease and Suicide: An Integrative Literature Review

被引：0

作者：

Rodrigues, Juliano Flavio Rubatino ^{[1
,2
,3
]}

Rodrigues, Livia Peregrino ^{[4
,5
]}

de Araujo Filho, Gerardo Maria ^{[2
]}

机构：

[1] Fac Med Marilia FAMEMA, Marilia, SP, Brazil

[2] Fac Med Sao Jose do Rio Preto FAMERP, Sao Jose Do Rio Preto, SP, Brazil

[3] Unimed Bauru Cooperat Trabalho Med, Bauru, SP, Brazil

[4] Fac Med Barbacena FAME, Barbacena, MG, Brazil

[5] Univ Marilia UNIMAR, Fac Med, Marilia, SP, Brazil

来源：

CURRENT ALZHEIMER RESEARCH | 2023年 / 20卷 / 11期

关键词：

Alzheimer's disease; suicide; review; integrative; old people; psychiatry; TO; 40; YEARS; INTERPERSONAL THEORY; APOE4; CARRIERS; MURDER SUICIDE; DEMENTIA; RISK; ASSOCIATION; DEPRESSION; EUTHANASIA; HISTORY;

D O I：

10.2174/0115672050292472240216052614

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction Suicide has been described in patients with Alzheimer's disease. Some promising medications for treating Alzheimer's disease have had their studies suspended because they increase the risk of suicide. Understanding the correlations between suicide and Alzheimer's disease is essential in an aging world.Method A search was carried out on electronic websites (PubMed and Scielo) using the MeSH Terms "suicide" and "Alzheimer" (1986-2023). Of a total of 115 articles, 26 were included in this review.Results Depression and the allele epsilon 4 of Apolipoprotein (APOE4) were demonstrated to be the main risk factors for suicide in patients with Alzheimer's disease.Conclusion Adequately delineating which elderly people are vulnerable to suicide is important so that new treatments for Alzheimer's disease can be successful. This review showed a need for new studies to investigate the interface between Alzheimer's disease and suicide.

引用

页码：758 / 768

页数：11

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