Obstructive Sleep Apnoea: A Shrouded High-Risk Association for Development of Hypertensive Disorders of Pregnancy

被引:1
作者
Sarbhai, Vinita [1 ]
Paswan, Pooja [2 ]
Sarbhai, Vikram [3 ]
机构
[1] Kasturba Med Coll & Hosp, Dept Gynecol & Obstet, C-36,First Floor, Delhi 110048, India
[2] Kasturba Med Coll & Hosp, Dept Obstet & Gynecol, Delhi, India
[3] Natl Heart Inst, East Kailash, New Delhi, India
关键词
Hypertensive disorders of pregnancy (HDP); Preeclampsia; Sleep-disordered breathing (SDB); Obstructive sleep Apnoea (OSA); Stop-Bang Questionnaire; Berlin Questionnaire; QUESTIONNAIRE; DISEASE;
D O I
10.1007/s13224-023-01835-y
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Background This objective of this study was to diagnose Obstructive Sleep Apnoea (OSA) in pregnant women using Questionnaire-based methods and to determine any association of Sleep-Disordered Breathing (SDB) with Hypertensive Disorder of Pregnancy (HDP). Additionally, the study aimed to identify factors associated with OSA.Methods This case-control study was conducted in department of Obstetrics in tertiary care hospital in Delhi. We Identified SDB using Berlin Questionnaire and Modified Stop-Bang Questionnaire in 100 pregnant women with Hypertension and 100 normotensive controls. We compared the groups using appropriate statistical analysis.Results The mean age of women with HDP (25.46 +/- 4.38) was found to be slightly higher than controls (24.13 +/- 3.89) (p value-0.02). Sleep apnoea as depicted by the presence of either high-risk STOP Bang or Berlin score was seen more often in hypertensive women in 45% as compared to controls in 8% (p value < 0.001). Higher pre-pregnancy weight (58.58 +/- 9.77 vs. 53.0 +/- 6.59), higher BMI (24.03 +/- 5.89 vs. 20.68 +/- 1.49), higher mean neck circumference (14.97 vs. 14.27 inches) weight gain more than 11 kg during pregnancy (55.6% vs. 38.2%) were the high-risk factors more commonly associated with SDB as seen in women with OSA in hypertensive women. On logistic regression analysis, the presence of OSA was singularly responsible for development of Hypertension (Odds Ratio-13.014, 95% CI 5.237-32.337) (p value < 0.001).Conclusion Gestational hypertension appears to be strongly associated with the presence of obstructive sleep apnoea. The recognition and treatment of OSA during pregnancy may lead to improved outcomes.
引用
收藏
页码:391 / 396
页数:6
相关论文
共 15 条
  • [1] The hypertensive disorders of pregnancy: ISSHP classification, diagnosis & management recommendations for international practice
    Brown, Mark A.
    Magee, Laura A.
    Kenny, Louise C.
    Karumanchi, S. Ananth
    McCarthy, Fergus P.
    Saito, Shigeru
    Hall, David R.
    Warren, Charlotte E.
    Adoyi, Gloria
    Ishaku, Salisu
    [J]. PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH, 2018, 13 : 291 - 310
  • [2] Obstructive sleep apnoea and its association with gestational hypertension
    Champagne, K.
    Schwartzman, K.
    Opatrny, L.
    Barriga, P.
    Morin, L.
    Mallozzi, A.
    Benjamin, A.
    Kimoff, R. J.
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2009, 33 (03) : 559 - 565
  • [3] Sleep-disordered breathing and upper airway size in pregnancy and post-partum
    Izci, B
    Vennelle, M
    Liston, WA
    Dundas, KC
    Calder, AA
    Douglas, NJ
    [J]. EUROPEAN RESPIRATORY JOURNAL, 2006, 27 (02) : 321 - 327
  • [4] Sleep complaints: snoring and daytime sleepiness in pregnant and pre-eclamptic women
    Izci, B
    Martin, SE
    Dundas, KC
    Liston, WA
    Calder, AA
    Douglas, NJ
    [J]. SLEEP MEDICINE, 2005, 6 (02) : 163 - 169
  • [5] Using the Berlin Questionnaire to identify patients at risk for the sleep apnea syndrome
    Netzer, NC
    Stoohs, RA
    Netzer, CM
    Clark, K
    Strohl, KP
    [J]. ANNALS OF INTERNAL MEDICINE, 1999, 131 (07) : 485 - +
  • [6] Relation of sleep-disordered breathing to cardiovascular disease risk factors - The Sleep Heart Health Study
    Newman, AB
    Nieto, FJ
    Guidry, U
    Lind, BK
    Redline, S
    Shahar, E
    Pickering, TG
    Quan, SF
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 2001, 154 (01) : 50 - 59
  • [7] Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: prospective cohort study
    O'Brien, Louise M.
    Bullough, Alexandra S.
    Owusu, Jocelynn T.
    Tremblay, Kimberley A.
    Brincat, Cynthia A.
    Chames, Mark C.
    Kalbfleisch, John D.
    Chervin, Ronald D.
    [J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2012, 207 (06) : 487.e1 - 487.e9
  • [8] The STOP-Bang Questionnaire as a Screening Tool for Obstructive Sleep Apnea in Pregnancy
    Pearson, Fiona
    Batterham, Alan M.
    Cope, Sean
    [J]. JOURNAL OF CLINICAL SLEEP MEDICINE, 2019, 15 (05): : 705 - 710
  • [9] Preeclampsia, a Disease of the Maternal Endothelium The Role of Antiangiogenic Factors and Implications for Later Cardiovascular Disease
    Powe, Camille E.
    Levine, Richard J.
    Karumanchi, S. Ananth
    [J]. CIRCULATION, 2011, 123 (24) : 2856 - 2869
  • [10] Pregnant Women with Gestational Hypertension May Have a High Frequency of Sleep Disordered Breathing
    Reid, John
    Skomro, Robert
    Cotton, David
    Ward, Heather
    Olatunbosun, Femi
    Gjevre, John
    Guilleminault, Christian
    [J]. SLEEP, 2011, 34 (08) : 1033 - 1038