Hypertensive disorders of pregnancy (HDP);
Preeclampsia;
Sleep-disordered breathing (SDB);
Obstructive sleep Apnoea (OSA);
Stop-Bang Questionnaire;
Berlin Questionnaire;
QUESTIONNAIRE;
DISEASE;
D O I:
10.1007/s13224-023-01835-y
中图分类号:
R71 [妇产科学];
学科分类号:
100211 ;
摘要:
Background This objective of this study was to diagnose Obstructive Sleep Apnoea (OSA) in pregnant women using Questionnaire-based methods and to determine any association of Sleep-Disordered Breathing (SDB) with Hypertensive Disorder of Pregnancy (HDP). Additionally, the study aimed to identify factors associated with OSA.Methods This case-control study was conducted in department of Obstetrics in tertiary care hospital in Delhi. We Identified SDB using Berlin Questionnaire and Modified Stop-Bang Questionnaire in 100 pregnant women with Hypertension and 100 normotensive controls. We compared the groups using appropriate statistical analysis.Results The mean age of women with HDP (25.46 +/- 4.38) was found to be slightly higher than controls (24.13 +/- 3.89) (p value-0.02). Sleep apnoea as depicted by the presence of either high-risk STOP Bang or Berlin score was seen more often in hypertensive women in 45% as compared to controls in 8% (p value < 0.001). Higher pre-pregnancy weight (58.58 +/- 9.77 vs. 53.0 +/- 6.59), higher BMI (24.03 +/- 5.89 vs. 20.68 +/- 1.49), higher mean neck circumference (14.97 vs. 14.27 inches) weight gain more than 11 kg during pregnancy (55.6% vs. 38.2%) were the high-risk factors more commonly associated with SDB as seen in women with OSA in hypertensive women. On logistic regression analysis, the presence of OSA was singularly responsible for development of Hypertension (Odds Ratio-13.014, 95% CI 5.237-32.337) (p value < 0.001).Conclusion Gestational hypertension appears to be strongly associated with the presence of obstructive sleep apnoea. The recognition and treatment of OSA during pregnancy may lead to improved outcomes.
机构:
St George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Univ NSW, St George Hosp, Clin Sch, Dept Med, Sydney, NSW, AustraliaSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Brown, Mark A.
Magee, Laura A.
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h-index: 0
机构:
Kings Coll London, Fac Life Sci & Med, London, EnglandSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Magee, Laura A.
Kenny, Louise C.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Liverpool, Fac Hlth & Life Sci, Liverpool, Merseyside, England
Cork Univ, Matern Hosp, INFANT Ctr, Cork, IrelandSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Kenny, Louise C.
Karumanchi, S. Ananth
论文数: 0引用数: 0
h-index: 0
机构:
Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA
Harvard Med Sch, Boston, MA USASt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Karumanchi, S. Ananth
McCarthy, Fergus P.
论文数: 0引用数: 0
h-index: 0
机构:
Cork Univ, Matern Hosp, INFANT Ctr, Cork, IrelandSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
McCarthy, Fergus P.
Saito, Shigeru
论文数: 0引用数: 0
h-index: 0
机构:
Univ Toyama, Grad Sch Med & Pharmaceut Sci Res, Dept Obstet & Gynecol, Toyama, JapanSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Saito, Shigeru
Hall, David R.
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h-index: 0
机构:
Stellenbosch Univ, Dept Obstet & Gynaecol, Tygerberg, South Africa
Tygerberg Hosp, Tygerberg, South AfricaSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Hall, David R.
Warren, Charlotte E.
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h-index: 0
机构:
Populat Council, Reprod Hlth Program, Washington, DC USASt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Warren, Charlotte E.
Adoyi, Gloria
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h-index: 0
机构:
Populat Council, Reprod Hlth Program, West Africa, NigeriaSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Adoyi, Gloria
Ishaku, Salisu
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h-index: 0
机构:
Populat Council, Reprod Hlth Program, West Africa, NigeriaSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
机构:
Harvard Univ, Sch Med, Boston, MA USABeth Israel Deaconess Med Ctr, Ctr Vasc Biol, Howard Hughes Med Inst, Boston, MA 02215 USA
Powe, Camille E.
Levine, Richard J.
论文数: 0引用数: 0
h-index: 0
机构:
Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, US Dept HHS, Div Epidemiol Stat & Prevent Res, Bethesda, MD USABeth Israel Deaconess Med Ctr, Ctr Vasc Biol, Howard Hughes Med Inst, Boston, MA 02215 USA
Levine, Richard J.
Karumanchi, S. Ananth
论文数: 0引用数: 0
h-index: 0
机构:
Beth Israel Deaconess Med Ctr, Ctr Vasc Biol, Howard Hughes Med Inst, Boston, MA 02215 USA
Harvard Univ, Sch Med, Boston, MA USABeth Israel Deaconess Med Ctr, Ctr Vasc Biol, Howard Hughes Med Inst, Boston, MA 02215 USA
机构:
St George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Univ NSW, St George Hosp, Clin Sch, Dept Med, Sydney, NSW, AustraliaSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Brown, Mark A.
Magee, Laura A.
论文数: 0引用数: 0
h-index: 0
机构:
Kings Coll London, Fac Life Sci & Med, London, EnglandSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Magee, Laura A.
Kenny, Louise C.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Liverpool, Fac Hlth & Life Sci, Liverpool, Merseyside, England
Cork Univ, Matern Hosp, INFANT Ctr, Cork, IrelandSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Kenny, Louise C.
Karumanchi, S. Ananth
论文数: 0引用数: 0
h-index: 0
机构:
Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02215 USA
Harvard Med Sch, Boston, MA USASt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Karumanchi, S. Ananth
McCarthy, Fergus P.
论文数: 0引用数: 0
h-index: 0
机构:
Cork Univ, Matern Hosp, INFANT Ctr, Cork, IrelandSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
McCarthy, Fergus P.
Saito, Shigeru
论文数: 0引用数: 0
h-index: 0
机构:
Univ Toyama, Grad Sch Med & Pharmaceut Sci Res, Dept Obstet & Gynecol, Toyama, JapanSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Saito, Shigeru
Hall, David R.
论文数: 0引用数: 0
h-index: 0
机构:
Stellenbosch Univ, Dept Obstet & Gynaecol, Tygerberg, South Africa
Tygerberg Hosp, Tygerberg, South AfricaSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Hall, David R.
Warren, Charlotte E.
论文数: 0引用数: 0
h-index: 0
机构:
Populat Council, Reprod Hlth Program, Washington, DC USASt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Warren, Charlotte E.
Adoyi, Gloria
论文数: 0引用数: 0
h-index: 0
机构:
Populat Council, Reprod Hlth Program, West Africa, NigeriaSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
Adoyi, Gloria
Ishaku, Salisu
论文数: 0引用数: 0
h-index: 0
机构:
Populat Council, Reprod Hlth Program, West Africa, NigeriaSt George Hosp, Dept Renal Med, Sydney, NSW 2217, Australia
机构:
Harvard Univ, Sch Med, Boston, MA USABeth Israel Deaconess Med Ctr, Ctr Vasc Biol, Howard Hughes Med Inst, Boston, MA 02215 USA
Powe, Camille E.
Levine, Richard J.
论文数: 0引用数: 0
h-index: 0
机构:
Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, US Dept HHS, Div Epidemiol Stat & Prevent Res, Bethesda, MD USABeth Israel Deaconess Med Ctr, Ctr Vasc Biol, Howard Hughes Med Inst, Boston, MA 02215 USA
Levine, Richard J.
Karumanchi, S. Ananth
论文数: 0引用数: 0
h-index: 0
机构:
Beth Israel Deaconess Med Ctr, Ctr Vasc Biol, Howard Hughes Med Inst, Boston, MA 02215 USA
Harvard Univ, Sch Med, Boston, MA USABeth Israel Deaconess Med Ctr, Ctr Vasc Biol, Howard Hughes Med Inst, Boston, MA 02215 USA