A graphene oxide/Zn-metal organic framework electrochemical sensor for acetaminophen detection

被引:42
作者
Wang, Shujun [1 ,2 ]
Chen, Fengping [2 ]
Li, Zhi [3 ]
Tao, Huan [2 ]
Qu, Liangzhuo [1 ]
Li, Jinhua [4 ,5 ]
Zhu, Mingshan [1 ,3 ]
Zha, Qingbing [1 ,2 ]
机构
[1] Jinan Univ, Heyuan Shenhe Peoples Hosp, Dept Clin Lab, Affiliated Hosp 5, Heyuan 517000, Peoples R China
[2] Jinan Univ, Dept Clin Lab, Affiliated Hosp 1, Guangzhou 510630, Peoples R China
[3] Jinan Univ, Sch Environm, Guangzhou 511443, Peoples R China
[4] Jinan Univ, Heyuan Shenhe Peoples Hosp, Dept Ultrasound, Affiliated Hosp 5, Heyuan 517000, Peoples R China
[5] Jinan Univ, Dept Ultrasound, Affiliated Hosp 1, Guangzhou 510630, Peoples R China
关键词
Graphene oxide; Zn-metal organic framework; Electrochemical sensor; Acetaminophen detection; Electron transfer; BISPHENOL-A; ADSORPTION; ELECTRODE; IMPACT;
D O I
10.1016/j.surfin.2023.102910
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
In this study, an electrochemical sensor based on graphene oxide (GO)/Zn-metal organic framework (ZIF-8) composite electrode was used to detect acetaminophen (APAP). GO/ZIF-8 was characterized by X-ray diffraction, transmission electron microscope, and X-ray photoelectron spectroscopy. The electrochemical behavior of APAP on GO/ZIF-8 modified glassy carbon electrode (GCE) was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The DPV signal of GO/ZIF-8 for APAP detection is 4.3 times higher than pure ZIF-8, and the efficient electrochemical performance was attributed to that introduction of GO can effectively enhance the electron transport capacity of ZIF-8. The sensor exhibits a linear range of 0.05-1.3 mu M and a low detection limit of 0.014 mu M. It shows excellent selectivity, repeatability and also can be used to determine APAP in human urine samples and drug tablets.
引用
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页数:7
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