DEVELOPING AN EXTREMELY HIGH FLOW RATE PNEUMATIC PERISTALTIC MICROPUMP FOR BLOOD PLASMA SEPARATION WITH INERTIAL PARTICLE FOCUSING TECHNIQUE FROM FINGERTIP BLOOD WITH LANCETS

被引：1

作者：

Vo, Tuan N. A. ^{[1
,2
,3
]}

Chen, Pin-Chuan ^{[1
]}

Chen, Pai-Shan ^{[4
]}

机构：

[1] Natl Taiwan Univ Sci & Technol, Dept Mech Engn, Taipei, Taiwan

[2] Ho Chi Minh City Univ Technol HCMUT, Fac Mech Engn, 268 Ly Thuong Kiet St,Dist 10, Ho Chi Minh City, Vietnam

[3] Vietnam Natl Univ Ho Chi Minh City VNU HCM, Linh Trung Ward, Ho Chi Minh City, Vietnam

[4] Natl Taiwan Univ, Inst Toxicol, Coll Med, Taipei, Taiwan

来源：

2023 IEEE 36TH INTERNATIONAL CONFERENCE ON MICRO ELECTRO MECHANICAL SYSTEMS, MEMS | 2023年

关键词：

Micropump; Inertial Microfluidics; Blood Plasma Separation; ULTRA-FAST;

D O I：

10.1109/MEMS49605.2023.10052216

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

This paper proposes an on-chip for blood plasma separation based on a pneumatic peristaltic micropump (PPM) linked to a spiral channel with a trapezoidal cross-section, which is used as an inertial particle focusing technique. The concept was based on the excellent bonding strength of PMMA/PDMS/PMMA and developed the PPM capable of delivering an extremely high flow rate of 3,500 mu L/min. The device rapidly extracts blood plasma from diluted blood within 3 minutes for four rounds, with an efficiency of 97%. The total volume needed for each extraction process was only 4 mu L whole blood drawn from a fingertip with a lancet.

引用

页码：1045 / 1048

页数：4

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